Results 141 to 150 of about 751,516 (267)

Voltage sensitivity of dopamine D2-like receptors

, 2011
G protein coupled receptors (GPCRs) mediate a multitude of responses serving hormonal, neurotransmitter, and sensory functions. These receptors are important drug targets; in fact, about 27 % of prescribed drugs are GPCR ligands. The dopamine D2 receptor
Kristoffer Sahlholm (18664273)
core   +1 more source

Dopamine D2 receptor [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Crosstalk Between Cortical Plasticity and Peripheral Nervous Injury: Insights, Mechanisms, and Future Directions

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Peripheral nerve injury induces dynamic cortical plasticity, driven by molecular mechanisms such as BDNF and neurotransmitter systems. This review synthesizes subtype‐specific plasticity patterns: compressive injuries trigger rapid reorganization, while metabolic neuropathies lead to maladaptive changes.
Cong Cheng, Dong Gao, Yaojie Shen, Xi Wang, Junxi Dai, Yaoxian Xiang, Zongyuan Jiang, Zongqi You, Junjian Jiang   +8 more
wiley   +1 more source

Dopaminergic Dysregulation in Migraine: From Hypothalamic A11 Dysfunction to a Systemic Biobehavioral Phenotype. [PDF]

Int J Mol Sci
Przegrałek J, Targosiński F, Marschollek K, Łaczmańska I, Pellesi L, Budrewicz S, Nowakowska-Kotas M, Waliszewska-Prosół M.   +7 more
europepmc   +1 more source

Smoking Abstinence Elicits Hyperalgesia: Neural Mechanism, Clinical Implications, and Pharmacological Managements

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
The cycle between nicotine use and pain modulation. Cigarette smoking leads to nicotine entering the body, which binds to nicotinic acetylcholine receptors (nAChRs) in the brain, triggering the release of different neurotransmitters, including dopamine (DA), norepinephrine (NE), serotonin (5‐HT), and GABA.
Shan‐shan Hu, Chao‐feng Zhang, Battuvshin Lkhagvasuren, Di Wang   +3 more
wiley   +1 more source

ZnO Decorated Electrospun Polylactic Acid Membrane for Organic Dyes Removal From Wastewaters

EcoMat, Volume 8, Issue 9, September 2026.
PLA electrospun membranes doped with ZnO can spontaneously remove organic dyes from wastewater. The high adsorption capacity obtained is strongly influenced by environmental conditions. ABSTRACT The present work reports the design of a novel nanocomposite adsorbent based on a bio‐based PLA electrospun membrane doped with ZnO (28 wt% confirmed by TGA ...
Gianluca Viscusi, Marta Balsamo, Maria Chiara Mistretta, Giuliana Gorrasi, Roberto Scaffaro   +4 more
wiley   +1 more source

Quantifying Heteromer Partitioning Reveals Inflammation‐Dependent Redistribution of Microglial Adenosine A2A and Cannabinoid CB2 Receptors

Glia, Volume 74, Issue 9, September 2026.
Proinflammatory activation reorganizes microglial A2A and CB2 receptors, promoting their incorporation into stable heteromers and blocking agonist‐induced redistribution. The results reveal those heteromers as potential therapeutic targets in inflammatory contexts.
Rafael Franco, Jaume Lillo, Christian Griñán‐Ferré, Mercè Pallàs, Rafael Rivas‐Santisteban   +4 more
wiley   +1 more source

Psilocybin, From Ancestral Use to Therapeutic Potential: A Multidimensional Review of Its Pharmacological Basis and Current Perspectives

Human Psychopharmacology: Clinical and Experimental, Volume 41, Issue 5, September 2026.
ABSTRACT Objective This review critically examines psilocybin, with particular emphasis on its pharmacokinetics and pharmacodynamics, including its serotonergic, neuroplastic, and anti‐inflammatory mechanisms. It integrates historical context, preclinical and clinical evidence, and evaluates emerging therapeutic potential, safety, microdosing practices,
José Norberto Vásquez‐Bonilla
wiley   +1 more source

The Synaptic Vesicle Priming Protein Munc13 Mediates Evoked Somatodendritic Dopamine Release. [PDF]

J Neurosci
Lebowitz JJ, Banerjee A, Handy G, Williams JT, Kaeser PS.   +4 more
europepmc   +1 more source

Dopamine D2 receptor ligands

, 2017
The present invention relates to novel dopamine D2 receptor ligands. The invention further relates to functionally-biased dopamine D2 receptor ligands and the use of these compounds for treating or preventing central nervous system and systemic disorders
DORDEVIC, Luka, ZHANG, Yan-Ling, WAGNER Florence, SCOLNICK, Edward, HOLSON, Edward, PALMER, Michelle, Fevrier, XU, Qihong, WEIWER, Michel, LEWIS, Michael, PAN Jennifer   +10 more
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