Altered functional connectivity of basal forebrain subregions (Ch1‐3, Ch4) and widespread cerebral hypometabolism were identified in Alzheimer's disease using simultaneous PET/MRI. Spatial correspondence with normative neurotransmitter receptor and transporter maps suggested that serotonergic and dopaminergic systems may contribute to AD‐related ...
Yujie He +11 more
wiley +1 more source
Disruption of Dopamine Homeostasis by Psychostimulants. [PDF]
Torres J +3 more
europepmc +1 more source
Oncogenic driver and therapeutic target: Prolactin signalling axis in retroperitoneal sarcoma
Retroperitoneal sarcoma cells can secrete prolactin into the bloodstream, inducing hyperprolactinaemia, which subsequently triggers metabolic reprogramming, such as glucose metabolism. SOX4 can function as a transcription factor that facilitates PRL transcription.
Fu'an Xie +21 more
wiley +1 more source
Involvement of D1- and D2-like dopamine receptors in the hippocampal CA1 region in mediating the restraint stress-induced analgesia in the rats. [PDF]
Shirmohammadi D +3 more
europepmc +1 more source
Organic neuromorphic electronics powering intelligent sensory and edge computing systems
Organic electronic materials are promising candidates for neuromorphic sensing applications, including chemical, physical, visual, and multimodal sensing, owing to their mechanical softness, biocompatibility, and intrinsic ionic–electronic coupling.
Seungjun Woo +5 more
wiley +1 more source
Mechanistic Insights of Zonisamide in Parkinson's Disease: A Systematic Review
ABSTRACT Zonisamide is an antiepileptic agent used as adjunctive therapy for Parkinson's Disease in Japan and studied more selectively elsewhere. Preclinical and early translational studies suggest that zonisamide may modulate several pathways relevant to Parkinson's Disease pathobiology, including dopaminergic neurotransmission, oxidative stress ...
Justin Kim +3 more
wiley +1 more source
Dopamine D2-receptor blockade in humans disrupts the effect of effort on learning. [PDF]
Jarvis H +5 more
europepmc +1 more source
Dopamine D2 Receptor Dimer Formation [PDF]
Duncan Armstrong, Philip G. Strange
openaire +1 more source
Abstract Background and Purpose Subsets of midbrain dopamine (DA) neurons express the vesicular glutamate transporter VGLUT2 and can release the excitatory neurotransmitter glutamate. VGLUT2+ DA neurons of the substantia nigra pars compacta (SNc) were shown to be more resistant to neurodegeneration in animal models of Parkinson's disease (PD ...
Sivakumar Srinivasan +2 more
wiley +1 more source
Lower Striatal Dopamine D2 Receptor Availability in Individuals Who Test Positive for Quantitated Urine Metabolites of Tobacco and/or Marijuana Smoke. [PDF]
Yoder KK +4 more
europepmc +1 more source

