Results 151 to 160 of about 80,664 (276)
In female mice, estrogen withdrawal following a hormone‐simulated pseudopregnancy is associated with increased levels of ∆FOSB in the Nucleus Accumbens Core and increased anxiety behaviors. However, using viral‐mediated expression of ∆JUND to decrease ∆FOSB‐mediated transcription in the Nucleus Accumbens Core prevents the increase in anxiety following ...
Willow Clayton +9 more
wiley +1 more source
ABSTRACT Introduction Burning mouth syndrome (BMS) is occasionally accompanied by denture intolerance. Case Presentation An 80‐year‐old woman with complaints of residual and relapsed intraoral pain and denture intolerance due to BMS was improved by olanzapine without severe adverse events, and her eating ability was successfully restored.
Motoko Watanabe +7 more
wiley +1 more source
Interplay between VEGF‐A‐driven angiogenesis and DRD2‐mediated inhibition. Tumor‐derived VEGF‐A activates VEGFR2 on endothelial cells, triggering proangiogenic signaling pathways that promote abnormal vessel growth and vascular leakage. VEGF‐A also induces DRD2 expression, establishing a feedback mechanism.
Venu Akkanapally +6 more
wiley +1 more source
Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source
NAD+‒circadian rhythm coupling in dementia
Abstract The circadian rhythm system and sleep coordinate whole‐body functions across the 24‐h cycle, yet these rhythms progressively deteriorate with neurodegenerative diseases, including dementia. Growing evidence indicates that nicotinamide adenine dinucleotide (NAD+) interacts with the circadian system through multiple molecular pathways and that ...
Shi‐qi Zhang +7 more
wiley +1 more source
Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou +2 more
wiley +1 more source
ABSTRACT In heart failure patients, dopamine therapy, particularly at higher doses, may induce seizures due to its impact on cerebral blood flow and exacerbation of underlying hypoxemia and electrolyte imbalances. Close monitoring and cautious use of dopamine, with consideration of alternative inotropic agents like dobutamine, are essential to mitigate
Chuanwei Zhao +4 more
wiley +1 more source
Long‐term clinical course of a patient with geriatric depression presenting with levodopa‐responsive pseudoparkinsonism over a 3‐year follow‐up period. ABSTRACT Geriatric depression often presents with psychomotor retardation. Severe psychomotor retardation may manifest as pseudoparkinsonism, which mimics Parkinson's disease (PD) and is often difficult
Kenshiro Imaizumi +9 more
wiley +1 more source

