Our results demonstrate massive degeneration of tyrosine hydroxylase‐immunoreactive neurons was observed in the SNpc, striatum, and ventral tegmental area with 6‐OHDA infusions in either the SNpc or striatum. Rats administered 6‐OHDA to the SNpc exhibited cognitive impairments, anxiety‐like behaviors, and impacted the maturation of newborn hippocampal ...
Bianca Andretto de Mattos +4 more
wiley +1 more source
Dopamine receptors in ocular surface biology: Current evidence and future directions. [PDF]
Shetty R +6 more
europepmc +1 more source
Cancer Neuroscience: From Local Neuro–Immune Microenvironments to Systemic Brain–Body Circuitry
This review outlines the cancer neuroscience paradigm, spanning systemic brain–body circuitry and local neuro–immune–tumor microenvironments. We discuss how tumors promote axonogenesis and pseudo‐synapse formation, and how sensory neuropeptides, such as CGRP, contribute to CD8+ T‐cell exhaustion.
Mingxuan Xie +7 more
wiley +1 more source
Cardiovascular pharmacology of dopaminergic agents in humans: a review. [PDF]
Palma JA, Gomez Casanovas JG.
europepmc +1 more source
Digital and Biomarker‐Based Monitoring for Schizophrenia‐Treatment Adherence
Monitoring technologies integrated with artificial intelligence can enable personalized care, improved adherence, and reduced relapses among psychotic patients. ABSTRACT Background Nonadherence to antipsychotics affects nearly half of patients with schizophrenia, leading to rehospitalization, suicidality, and reduced quality of life.
Samuel Inshutiyimana +5 more
wiley +1 more source
Atropine reinstates inflammation-induced dysregulation of dopamine and its receptors in human scleral cells: Implications for myopia therapy. [PDF]
Shivakumar S +6 more
europepmc +1 more source
Synergistic “Double Brake” Model on the Spinal Defecation Center in Clozapine‐Induced Constipation. Real‐world data shows BZDRs increase laxative risk in schizophrenia. Mitigating the central GABAergic brake via sedative optimization and maintaining gut microbiota homeostasis prevents fatal Ogilvie's syndrome.
Takahiko Nagamine
wiley +1 more source
Tryptophan Supplementation Reduces Schizophrenia-Like Symptoms in Apomorphine Treated Rats: Role of D2, GABA, and Glutamate Receptor Expression. [PDF]
Nawaz S +5 more
europepmc +1 more source
Neurotensin as Modulator of Glutamatergic Signalling: Relevance in Neurodegenerative Diseases
Rationale: Neurotensin (NT) is a tridecapeptide widely distributed in mammalian brain, where acts as a neurotransmitter or neuromodulator of classical neurotransmitters, mainly through the activation of its receptor NTS1.
Mazza, Roberta
core
Increased Libido Following Brivaracetam Initiation: A Case Report of Temporal Lobe Epilepsy
This case report highlights a patient with temporal lobe epilepsy who experienced a distressing libido increase following brivaracetam initiation. Although primarily associated with brivaracetam, incomplete Klüver–Bucy syndrome and concurrent brexpiprazole may have also been involved.
Toru Horinouchi +4 more
wiley +1 more source

