Results 171 to 180 of about 150,460 (322)

Role of Dopamine D2 Receptors in Human Reinforcement Learning

Neuropsychopharmacology, 2014
C. Eisenegger, Michael Naef, A. Linssen, L. Clark, P. K. Gandamaneni, U. Müller, T. Robbins   +6 more
semanticscholar   +1 more source

Overexpression of the short isoform of the dopamine D2 receptor causes diet‐induced obesity and hyperglycemia in mice

Journal of Neuroendocrinology, EarlyView.
Alterations in the expression levels of D2S and D2L resulted in obesity and metabolic syndrome such as abdominal fat accumulation and hyperglycemia in D2L KO mice fed with a high‐fat diet, compared to WT mice. This may be partly due to increased food intake.
Hanna Gonzalez, Lei Cheng, Qing Chang, Paul E. Gold, Diego Perez‐Tilve, YanYan Wang   +5 more
wiley   +1 more source

Loss of choroid plexus‐derived insulin‐like growth factor 2 (IGF2) leads to hyposmia, while retaining post‐partum mood resilience in mice

Journal of Neuroendocrinology, EarlyView.
Abstract During the post‐partum period, new mothers are vulnerable to mood disorders. In adults, impairments in neurogenesis commonly associate with anxiety and depressive behaviors. Insulin‐like growth factor 2 (IGF2) is expressed in the choroid plexus (CP) within the subventricular zone (SVZ) neurogenic niche, and global loss of IGF2 leads to ...
Hollian R. Phillipps, Eleni C. R. Hackwell, Ionel Sandovici, Miguel Constância, David R. Grattan   +4 more
wiley   +1 more source

Aversive behavior induced by optogenetic inactivation of ventral tegmental area dopamine neurons is mediated by dopamine D2 receptors in the nucleus accumbens

Proceedings of the National Academy of Sciences of the United States of America, 2014
Teruko Danjo, K. Yoshimi, K. Funabiki, Satoshi Yawata, S. Nakanishi   +4 more
semanticscholar   +1 more source

Disrupted circadian rhythms and opioid‐mediated adverse effects: Bidirectional relationship and putative mechanisms

Journal of Neuroendocrinology, EarlyView.
Abstract Recent studies have shown a link between disrupted circadian rhythms and the development of chronic opioid‐induced negative effects. Both animal and human studies show a significant bidirectional relationship between the circadian system and opioid effects.
Nasrin Mehranfard, Maedeh Ghasemi, Ehsan Saboory   +2 more
wiley   +1 more source

Dopamine D2 receptor availability is linked to hippocampal–caudate functional connectivity and episodic memory

Proceedings of the National Academy of Sciences of the United States of America, 2016
L. Nyberg, Nina Karalija, Alireza Salami, M. Andersson, A. Wåhlin, Neda Kaboovand, Ylva Köhncke, J. Axelsson, A. Rieckmann, G. Papenberg, D. Garrett, K. Riklund, M. Lövdén, U. Lindenberger, L. Bäckman   +14 more
semanticscholar   +1 more source

Dopamine genetic risk scores and psychiatric symptoms: Interacting risk factors for impulse control behaviours in de novo Parkinson's disease

Journal of Neuropsychology, EarlyView.
Abstract Up to 45% of patients with Parkinson's disease (PD) experience impulse control disorders (ICDs), characterized by a loss of voluntary control over impulses, drives or temptations. This study aimed to investigate whether previously identified genetic and psychiatric risk factors interact towards the development of ICDs in PD.
Emma Whooley, Vincent Koppelmans, Hayley J. MacDonald, Alison Hall, Marit F. L. Ruitenberg   +4 more
wiley   +1 more source

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

Journal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer, Paulina Hoppa, Erzsébet Frank, Teadora Tyler, Istvan Adorjan   +4 more
wiley   +1 more source

Evidence for Noncanonical Neurotransmitter Activation: Norepinephrine as a Dopamine D2-Like Receptor Agonist

Molecular Pharmacology, 2016
Marta Sánchez-Soto, Alessandro Bonifazi, N. Cai, Michael P. Ellenberger, A. Newman, S. Ferré, Hideaki Yano   +6 more
semanticscholar   +1 more source

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet, Marie Netchitaïlo, Fanny Fabre, Elise Belaidi, Claire Arnaud, Anne‐Laure Borel, Patrick Levy, Jean‐Louis Pépin, Renaud Tamisier   +8 more
wiley   +1 more source