Results 181 to 190 of about 39,913 (215)

The sense and nonsense of antipsychotic combinations: A model for dopamine D<sub>2/3</sub> receptor occupancy. [PDF]

open access: yesTransl Psychiatry
Spangemacher M   +6 more
europepmc   +1 more source
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Dopamine D2 receptor signaling dynamics of dopamine D2-neurotensin 1 receptor heteromers

Biochemical and Biophysical Research Communications, 2013
Biochemical, histochemical and coimmunoprecipitation experiments have indicated the existence of antagonistic dopamine D2 (D2R) and neurotensin 1 (NTS1R) receptor-receptor interactions in the dorsal and ventral striatum indicating a potential role of these receptor-receptor interactions in Parkinson's disease and schizophrenia.
Borroto Escuela D. O.   +10 more
openaire   +2 more sources

Olfactory receptor neurons express D2 dopamine receptors

The Journal of Comparative Neurology, 1999
The role of the dopamine (DA) in the olfactory bulb (OB) was explored by determining which of the potential target cells express dopamine receptors (DARs). Previously, it was reported that D2-like DAR (D2, D3, and D4 subtypes) radioligand binding is restricted to the outer layers of the OB.
N L, Koster   +6 more
openaire   +2 more sources

D2 dopamine receptor gene and alcoholism

Journal of Psychiatric Research, 1993
An allelic association of the TAQ I A1 D2 dopamine receptor gene polymorphism has been found in homogeneous populations of alcoholics from France.
Stéphane Amadéo   +12 more
openaire   +2 more sources

Solubilized dopamine/neuroleptic receptors (D2-type)

Progress in Neuro-Psychopharmacology, 1981
Abstract 1. 1. Dopamine (D 2 -type) receptors were solubilized from striatum of three species (human, canine, calf) using digitonin. 2. 2. The receptors were labeled with 3 H-spiperone and assayed by Sephadex G-50 columns or polyethylene glycol precipitation. 3. 3. The soluble receptors from canine and human tissue had similar K d 's and
B K, Madras   +3 more
openaire   +2 more sources

Cerebellar dopamine D2 receptors regulate social behaviors

Nature Neuroscience, 2022
The cerebellum, a primary brain structure involved in the control of sensorimotor tasks, also contributes to higher cognitive functions including reward, emotion and social interaction. Although the regulation of these behaviors has been largely ascribed to the monoaminergic system in limbic regions, the contribution of cerebellar dopamine signaling in
Laura Cutando   +12 more
openaire   +4 more sources

The Dopamine D2 Receptor

1992
Dopamine is the dominant catecholamine neurotransmitter in the mammalian brain. It is found throughout the entire central nervous system, but is predominant in the nigrostriatal, mesolimbic, and tuberoinfundibular tracts (Creese et al., 1983). Dopamine exerts its effects through binding to two types of receptor, the D1 and D2 receptors (Kebabian and ...
Olivier Civelli   +4 more
openaire   +1 more source

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