Results 11 to 20 of about 150,460 (322)

Gray-Matter Volume, Midbrain Dopamine D2/D3 Receptors and Drug Craving in Methamphetamine Users [PDF]

Molecular Psychiatry, 2015
Dysfunction of the mesocorticolimbic system has a critical role in clinical features of addiction. Despite evidence suggesting that midbrain dopamine receptors influence amphetamine-induced dopamine release and that dopamine is involved in ...
M. Alda
semanticscholar   +6 more sources

Dopamine receptors in GtoPdb v.2023.1 [PDF]

, 2023
Dopamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Dopamine Receptors [373]) are commonly divided into D1-like (D1 and D5) and D2-like (D2, D3 and D4) families, where the endogenous agonist is ...
Beaulieu, Jean-Martin, Borrelli, Emiliana, Carlsson, Arvid, Caron, Marc G., Civelli, Olivier, Espinoza, Stefano, Fisone, Gilberto, Gainetdinov, Raul R., Grandy, David K., Kebabian, John W., Langer, Saloman Z., Missale, Maria Cristina, Neve, Kim A., Scatton, Bernard, Schwartz, Jean-Charles, Sedvall, Goran, Seeman, Philip, Sibley, David R., Sokoloff, Pierre, Spano, Pierre F., Van Tol, Hubert H. M.   +20 more
core   +2 more sources

Dystonia: sparse synapses for D2 receptors in striatum of a DYT1 knock-out mouse model [PDF]

, 2020
Dystonia pathophysiology has been partly linked to downregulation and dysfunction of dopamine D2 receptors in striatum. We aimed to investigate the possible morpho-structural correlates of D2 receptor downregulation in the striatum of a DYT1 Tor1a mouse ...
Biagioni, S., Cardarelli, S., D'angelo, V., Fusco, F. R., Giorgi, M., Mercuri, N. B., Paldino, E., Sancesario, G., Sorge, R.   +8 more
core   +1 more source

Purification of brain D2 dopamine receptor. [PDF]

The EMBO Journal, 1988
D2 dopamine receptors have been extracted from bovine brain using the detergent cholate and purified approximately 20,000-fold by affinity chromatography on haloperidol-sepharose and wheat germ agglutinin-agarose columns. The purified preparation contains D2 dopamine receptors as judged by the pharmacological specificity of [3H]spiperone binding to the
Williamson, RA, Worrall, S, Chazot, PL, Strange, PG   +3 more
openaire   +3 more sources

Cigarette Use and Striatal Dopamine D2/3 Receptors: Possible Role in the Link between Smoking and Nicotine Dependence. [PDF]

, 2016
BackgroundCigarette smoking induces dopamine release in the striatum, and smoking- or nicotine-induced ventral striatal dopamine release is correlated with nicotine dependence.
London, Edythe D, Mandelkern, Mark A, Okita, Kyoji   +2 more
core   +2 more sources

REDUCED EXPRESSION OF DOPAMINE D2-RECEPTORS ON PERIPHERAL BLOOD LYMPHOCYTES AS A MARKER FOR PROGRESSION OF SUBCORTICAL COGNITIVE IMPAIRMENTS

Zaporožskij Medicinskij Žurnal, 2013
Introduction. Peripheral blood lymphocytes (PBL) express neurotransmitter and neuropeptide receptors. The dopamine receptors in PBL may reflect the status of homologous brain receptors.
O. A. Levada , I. V. Dobrodub, A. V. Trailin   +2 more
doaj   +1 more source

A Concise Review of the Conflicting Roles of Dopamine-1 versus Dopamine-2 Receptors in Wound Healing

Molecules, 2017
Catecholamines play an important regulatory role in cutaneous wound healing. The exact role of dopamine in human epidermis has yet to be fully elucidated. Current published evidence describes its differential effects on two separate families of G protein
Alexandra R. Vaughn, Michael James Davis, Raja K. Sivamani, Roslyn Rivkah Isseroff   +3 more
doaj   +1 more source

Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice [PDF]

, 2008
Behavioral sensitization to psychostimulants manifests as an increased locomotor response with repeated administration. Dopamine systems are accepted to play a fundamental role in sensitization, but the role of specific dopamine receptor subtypes has not
Atkins, Baik, Battisti, Battisti, Boileau, Cador, Chiang, Crabbe, Crawford, de Wit, Down, Fleckenstein, Gabbay, Glickstein, Hamamura, Jones, Kalivas, Kamens, Karler, Karper, Kelly, Kelly, Kilty, Kuczenski, Kuribara, Kuribara, Kuribara, McDougall, Neve, Palmer, Phillips, Phillips, Pierce, Robinson, Ron, Rubinstein, Sax, Schmauss, Shen, Tanabe, Ujike, Vezina, Vezina, Xu, Xu, Xu, Xu, Yates   +47 more
core   +1 more source

Accumbens dopamine D2 receptors increase motivation by decreasing inhibitory transmission to the ventral pallidum

Nature Communications, 2018
Dopamine D2 receptors (D2Rs) in the nucleus accumbens (NAc) regulate motivated behavior, but the underlying neurobiological mechanisms remain unresolved.
E. Gallo, Jozsef Meszaros, Jeremy Sherman, M. Chohan, E. Teboul, Claire S. Choi, H. Moore, J. Javitch, C. Kellendonk   +8 more
semanticscholar   +1 more source

Stress-induced reduction of dorsal striatal D2 dopamine receptors prevents retention of a newly acquired adaptive coping strategy [PDF]

, 2017
The inability to learn an adaptive coping strategy in a novel stressful condition leads to dysfunctional stress coping, a marker of mental disturbances.
Cabib, Simona, Campus, Paolo, Canterini, Sonia, Fiorenza, Maria Teresa, Orsini, Cristina, PUGLISI ALLEGRA, Stefano   +5 more
core   +1 more source