Results 191 to 200 of about 147,933 (225)

The Role of Extrastriatal Dopamine D2 Receptors in Schizophrenia

Biological Psychiatry, 2006
Despite numerous studies on extrastriatal regions involved in schizophrenia, studies on the functional implications of dopamine (DA) D2 receptors in the extrastriatal regions, including the cortex and thalamus, are limited. We review postmortem and in vivo human imaging studies as well as animal studies, focusing on the function of extrastriatal DA D2 ...
Makoto Higuchi, Hidehiko Takahashi, Tetsuya Suhara   +2 more
openaire   +3 more sources

Dopamine D2 receptors in discrimination learning and spine enlargement

Nature, 2020
Y. Iino, Takeshi Sawada, K. Yamaguchi, Mio Tajiri, Shin Ishii, H. Kasai, Sho Yagishita   +6 more
semanticscholar   +1 more source

D2 dopamine receptor localization on striatonigral neurons

Neuroscience Letters, 1992
Two major pharmacological classes of dopamine receptors exist in the central nervous system. These receptors have been designated as D1 or D2 based upon their differing pharmacology and influence on the cyclic AMP second messenger system. Different genes for the D1 and D2 dopamine receptors have been isolated and are found to be expressed in high ...
David R. Sibley, Elzbieta M. Smyk-Randall, Marjorie A. Ariano, Christopher J. Stromski   +3 more
openaire   +3 more sources

Selective Dopamine D1 and D2 Receptor Antagonists

1989
The concept of selective dopamine D1 and D2 receptor antagonists is rather new. Previously, dopamine receptor antagonism was evaluated simply as the ability to inhibit dopamine- or dopamine agonist-mediated behaviour or biochemical responses. In 1979 Kebabian and Calne introduced the dopamine D1 and D2 receptor concept based on differential linkage to ...
J. Hyttel, J. Arnt, M. van den Berghe
openaire   +3 more sources

Neurobiological Features of Dopamine D2 Receptors

2002
Two different isoforms of the dopamine D2 receptor exist in vivo, named D2L and D2S. These isoforms are derived by alternative splicing of the sixth exon of the gene (Dal Toso et al., 1989; Giros et al., 1989). D2L is the longer isoform composed of 444 amino acids (aa) in rat (Monsma et al., 1989; Chio et al., 1990) and mouse (Montmayeur et al., 1991 ...
Ciro Iaccarino, Emiliana Borrelli, Alessandro Usiello   +2 more
openaire   +2 more sources

Isolation and characterization of D2-dopamine receptors

Biochemical Society Transactions, 1985
Strange, PG, Abbott, WM, Juszczak, R, Worrall, S   +3 more
openaire   +4 more sources

Adenosine A2A receptors, dopamine D2 receptors and their interactions in Parkinson's disease

, 2007
K. Fuxe, D. Marcellino, S. Genedani, L. Agnati   +3 more
semanticscholar   +1 more source

Activation of ventral tegmental area dopamine neurons produces wakefulness through dopamine D2-like receptors in mice

Brain Structure and Function, 2017
Yo Oishi, Yoshiaki Suzuki, Koji Takahashi, Toshiya Yonezawa, Takeshi Kanda, Yohko Takata, Y. Chérasse, M. Lazarus   +7 more
semanticscholar   +1 more source

A dopamine D2 receptor photolabel: Azidoclebopride

European Journal of Pharmacology, 1984
J.H. Guan, P. Seeman, Hyman B. Niznik, John L. Neumeyer   +3 more
openaire   +3 more sources

Structural analysis of the D2 dopamine receptor

Biochemical Society Transactions, 1992
Ursula M. D'Souza, Philip G. Strange
openaire   +3 more sources