Ex vivo stimulation of the trigeminal nucleus caudalis induces peripheral CGRP release in the trigeminal ganglion and reveals a distinct dopamine-endocannabinoid mechanism relevant to migraine. [PDF]
Christiansen IM+4 more
europepmc +1 more source
Oral Adverse Effects of Antipsychotic Medications: A Case/Noncase Analysis of EudraVigilance Data
ABSTRACT Objective Neuropsychiatric disorders are associated with poor oral health, with antipsychotics as potential contributors. This study aimed to analyse the oral adverse effects of antipsychotics using the EudraVigilance database. Methods A case/noncase analysis was conducted to calculate reporting odds ratios (ROR) and assess the ...
Leire Urien+5 more
wiley +1 more source
Using cocaine and apomorphine self-administration in rats to measure the pharmacokinetics of competitive dopamine receptor antagonists administered by different routes. [PDF]
Song HJ, Desai JN, Norman MK, Norman AB.
europepmc +1 more source
Neuroimmune pathophysiology of long COVID
Although COVID‐19 was originally considered a respiratory illness, it is now well established that SARS‐CoV‐2 infection can have far‐reaching impacts on the nervous system. Neurological symptoms such as chemosensory dysfunction are frequently observed during acute infection and approximately 10% of COVID‐19 cases will go on to develop new or persistent
Janna K. Moen+2 more
wiley +1 more source
A New Adjuvant Treatment for Glioblastoma Using Aprepitant, Vortioxetine, Roflumilast and Olanzapine: The AVRO Regimen. [PDF]
Kast RE+2 more
europepmc +1 more source
Early adversity and the comorbidity between metabolic disease and psychopathology
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas+1 more
wiley +1 more source
The interaction between social determinants of schizophrenia and brain dopamine circuitry. [PDF]
Selten JP, Schalbroeck R, Booij J.
europepmc +1 more source
Dual Control of Dopamine Synthesis and Release by Presynaptic and Postsynaptic Dopamine D2 Receptors
A. Anzalone+13 more
semanticscholar +1 more source
Mitochondrial control of ciliary gene expression and structure in striatal neurons
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen+5 more
wiley +1 more source
Rhabdomyolysis After Risperidone Overdose in a Patient With Schizophrenia: A Case Report
ABSTRACT A 50‐year‐old woman with schizophrenia overdosed on risperidone, lormetazepam, and lorazepam and subsequently developed rhabdomyolysis, with elevated creatine kinase (CK) and myoglobin levels. Intravenous treatment stabilized her condition. Risperidone was restarted at a regular dose, and rhabdomyolysis did not recur.
Jun Takahashi+5 more
wiley +1 more source