Results 231 to 240 of about 150,460 (322)

Suppression of mechanical hypersensitivity and change in the expression of the dopamine D2 receptor by administration of anti-CGRP antibody into the trigeminal ganglion in trigeminal neuropathic pain model rats. [PDF]

PLoS One
Maegawa H, Usami N, Kudo C, Niwa H.
europepmc   +1 more source

Adaptations of the Vertebrate Retina to Low‐Light Conditions: A Review

Anatomia, Histologia, Embryologia, Volume 54, Issue 4, July 2025.
ABSTRACT Vision is a critical sensory modality in vertebrates, enabling diverse adaptations to environmental challenges. This review explores the remarkable adaptations of vertebrate eyes to low‐light environments, such as nocturnal habitats, deep‐sea ecosystems and subterranean niches.
R. Cobo, A. Navarro‐Sempere, Y. Segovia, M. García   +3 more
wiley   +1 more source

The mechanism of action of clozapine. [PDF]

J Psychopharmacol
Morrison PD, Jauhar S, Young AH.
europepmc   +1 more source

Reversal of Diabesity Through Modulating Sympathetic Inputs to Adipose Tissue Following Carotid Body Resection

Acta Physiologica, Volume 241, Issue 7, July 2025.
ABSTRACT Background and Aims The development of innovative strategies to treat diabesity and its comorbidities is of major societal importance. The carotid bodies (CB), classically defined as O2 sensors, are also metabolic sensors whose dysfunction contributes to the genesis and progression of metabolic disturbances. Here, we tested the hypothesis that
Bernardete F. Melo, Joana F. Sacramento, Julien Lavergne, Fátima O. Martins, Daniela Rosendo‐Silva, Clara Panzolini, Cláudia S. Prego, Aidan Falvey, Elena Olea, Paulo Matafome, Asuncion Rocher, Jesus Prieto‐Lloret, Miguel C. Correia, Phillipe Blancou, Silvia V. Conde   +14 more
wiley   +1 more source

Striatal dopamine tone is positively associated with adiposity in humans as determined by PET using dual dopamine type-2 receptor antagonist tracers. [PDF]

Mol Psychiatry
Darcey VL, Guo J, Chi M, Chung ST, Courville AB, Gallagher I, Herscovitch P, Howard R, La Noire M, Milley L, Schick A, Stagliano M, Turner S, Urbanski N, Yang S, Yim E, Zhai N, Zhou MS, Hall KD.   +18 more
europepmc   +1 more source

Liquiritigenin‐Rich Hydroalcoholic Extract of Brazilian Red Propolis Reduces Dyskinesia Induced by 3,4‐ Dihydroxyphenylalanine in Hemiparkinsonian Rats

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 1, July 2025.
ABSTRACT The set‐up and progression of dyskinesia induced by 3,4‐dihydroxyphenylalanine (L‐DOPA) are strongly linked to oxidative stress and neuroinflammation. The aim of this work was to study and characterize the effects of the hydroalcoholic extract of Brazilian red propolis (HERP) on L‐DOPA–induced dyskinesia (LID) in hemiparkinsonian rats injected
Sheilla da Silva Barroso, Lorenna E. S. Lopes, Ana M. G. dos Santos, Reinaldo V. B. Neto, Bruno dos Santos Lima, Adriano A. de Souza Araújo, Juliana C. Cardoso, Patricia Severino, Eliana B. Souto, Margarete Z. Gomes   +9 more
wiley   +1 more source

Cranial radiation disrupts dopaminergic signaling and connectivity in the mammalian brain. [PDF]

Acta Neuropathol Commun
Zhang D, Thomas R, Lam TT, Veselinovic I, Grosshans DR.   +4 more
europepmc   +1 more source

Towards the convergent therapeutic potential of G protein‐coupled receptors in autism spectrum disorders

British Journal of Pharmacology, Volume 182, Issue 14, Page 3044-3067, July 2025.
Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi, Caroline Gora, Ana Dudas, Xavier Leray, Véronique Bozon, Pascale Crépieux, Lucie P. Pellissier   +6 more
wiley   +1 more source

Bromocriptine improves glucose tolerance in obese mice via central dopamine D2 receptor-independent mechanism. [PDF]

PLoS One
Tsuneki H, Maeda T, Takatsuki M, Sekine T, Masui S, Onishi K, Takeda R, Sugiyama M, Sakurai T, Yanagisawa M, Wada T, Sasaoka T.   +11 more
europepmc   +1 more source

Dopamine D2 receptors form higher order oligomers at physiological expression levels

EMBO Journal, 2008
Wen Guo, Eneko Urizar, M. Králíková, J. Mobarec, Lei Shi, M. Filizola, J. Javitch   +6 more
semanticscholar   +1 more source