Results 31 to 40 of about 39,913 (215)
British Journal of Clinical Pharmacology, EarlyView.Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
Central interaction of ascorbic acid and D2 dopamine receptors on spatial learning and memory in adult male rats [PDF]
The Iranian Journal of Veterinary Science and Technology, 2014 Previous studies had reported that extracellular levels of ascorbic acid have modulatory effects on dopamine receptors. Both ascorbic acid and dopamine receptor have an important role in learning and memory processes.
Sima Nasri +4 more
doaj +1 more source
Absence seizures: Update on signaling mechanisms and networks
Epilepsia Open, EarlyView.Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley +1 more source
BMC Neuroscience, 2007 Background In both schizophrenia and addiction, pathological changes in dopamine release appear to induce alterations in the circuitry of the nucleus accumbens that affect coordinated thought and motivation. Dopamine acts principally on medium-spiny GABA
Schmauss Claudia +2 more
doaj +1 more source
The role of intracerebral dopamine D1 and D2 receptors in sleep‐wake cycles and general anesthesia
Ibrain, 2022 Dopamine (DA), a monoamine neurotransmitter, is synthesized and released mainly by neurons in the ventral tegmental area and the substantia nigra (SN) pars compacta of the midbrain.
Jie Zhang +5 more
doaj +1 more source
Letter to the Editor: Dopamine D2S/D2L Receptor Regulation of Alcohol-Induced Reward and Signalling. [PDF]
Addict BiolAddiction Biology, Volume 31, Issue 1, January 2026.
Tariq M, Ahmad M, Hayat MZ, Khalid MH.
europepmc +2 more sources
Neurobiological correlates of obsessive‐compulsive disorder (OCD): A narrative review
Ibrain, EarlyView.Obsessive‐compulsive disorder (OCD) is a common and disabling, as well as underdiagnosed, neuropsychiatric condition characterized by involuntary and unwanted obsessions and/or compulsions often accompanied by states of severe anxiety, distress and shame, as well as other comorbid disorders. Despite the extensive literature available to date, only some
Giulio Perrotta, Anna Sara Liberati
wiley +1 more source
Dissociable effects of dopamine on neuronal firing rate and synchrony in the dorsal striatum
Frontiers in Integrative Neuroscience, 2009 Previous studies showed that dopamine depletion leads to both changes in firing rate and in neuronal synchrony in the basal ganglia. Since dopamine D1 and D2 receptors are preferentially expressed in striatonigral and striatopallidal medium spiny neurons,
John M Burkhardt +4 more
doaj +1 more source
iNew Medicine, EarlyView.In the freezing of gait in Parkinson's disease, white matter shows decreased local activity but increased functional connectivity. These distinct dysfunctions are uniquely associated with specific neurotransmitter systems (GABA, dopamine, etc.), mapping a new neurochemical basis for this debilitating symptom. ABSTRACT Freezing of gait (FOG) is a severe
Pingping Liu +10 more
wiley +1 more source
Tetrahydrocannabinol and dopamine D1 receptor
Frontiers in NeuroscienceDopamine, a neurotransmitter and neuromodulator, is primarily released by dopaminergic neurons in the midbrain, particularly in the substantia nigra and the ventral tegmental area (VTA).
Jiwon Lee
doaj +1 more source