Results 61 to 70 of about 150,460 (322)

Microfluidic Platform with Local Oxygen Sensors Demonstrates That 3D Blood Vessel Networks Exhibit Time‐Dependent Changes in Oxygen Concentrations During Their Formation and Perfusion

open access: yesAdvanced Materials Technologies, EarlyView.
Novel OoC platform with functional vascular networks highlights challenges in oxygenation. This study uses optical oxygen sensors to monitor oxygen during vascular formation, revealing perfusion limitations and highlighting the need for better oxygenation strategies.
Tarek Gensheimer   +5 more
wiley   +1 more source

Cloning and sequence analysis of brain cDNA encoding a Xenopus D2 dopamine receptor [PDF]

open access: yes, 1991
A D2 dopamine receptor pharmacologically different from the mammalian D2 receptor has previously been characterized in the amphibian Xenopus laevis. Here we report the cloning of a Xenopus D2 receptor which revealed about 75% amino acid sequence identity
Gröneveld, Diet   +3 more
core   +1 more source

Transformative 4D Printed SMPs into Soft Electronics and Adaptive Structures: Innovations and Practical Insights

open access: yesAdvanced Materials Technologies, EarlyView.
This review highlights recent advancements in 3DP techniques that incorporate emerging multifunctional SMP materials for applications in e‐electronics, soft actuators, biomedical devices, and more. Abstract Shape memory polymers (SMP) have recently gained significant attention as multifunctional materials for flexible and wearable electronics ...
Muhammad Yasir Khalid   +4 more
wiley   +1 more source

Distinct roles of presynaptic dopamine receptors in the differential modulation of the intrinsic synapses of medium-spiny neurons in the nucleus accumbens

open access: yesBMC Neuroscience, 2007
Background In both schizophrenia and addiction, pathological changes in dopamine release appear to induce alterations in the circuitry of the nucleus accumbens that affect coordinated thought and motivation. Dopamine acts principally on medium-spiny GABA
Schmauss Claudia   +2 more
doaj   +1 more source

Central interaction of ascorbic acid and D2 dopamine receptors on spatial learning and memory in adult male rats [PDF]

open access: yesThe Iranian Journal of Veterinary Science and Technology, 2014
Previous studies had reported that extracellular levels of ascorbic acid have modulatory effects on dopamine receptors. Both ascorbic acid and dopamine receptor have an important role in learning and memory processes.
Sima Nasri   +4 more
doaj   +1 more source

Reduced GABA-B/GIRK-mediated regulation of the VTA following a single exposure to cocaine [PDF]

open access: yes, 2012
In this paper, Arora and colleagues expand on their previous work on GIRK channels in the ventral tegmental area (VTA) presenting evidence that a single exposure to cocaine reduces inhibitory GABAergic transmission to dopamine (DA) neurons in the ventral
Andrew Varnell   +2 more
core   +2 more sources

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

open access: yesAdvanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich   +8 more
wiley   +1 more source

Dissociable effects of dopamine on neuronal firing rate and synchrony in the dorsal striatum

open access: yesFrontiers in Integrative Neuroscience, 2009
Previous studies showed that dopamine depletion leads to both changes in firing rate and in neuronal synchrony in the basal ganglia. Since dopamine D1 and D2 receptors are preferentially expressed in striatonigral and striatopallidal medium spiny neurons,
John M Burkhardt   +4 more
doaj   +1 more source

Striatal Dopamine D2/D3 Receptors Mediate Response Inhibition and Related Activity in Frontostriatal Neural Circuitry in Humans

open access: yesJournal of Neuroscience, 2012
Impulsive behavior is thought to reflect a traitlike characteristic that can have broad consequences for an individual's success and well-being, but its neurobiological basis remains elusive.
D. Ghahremani   +11 more
semanticscholar   +1 more source

Relationship of Alexithymia Ratings to Dopamine D2-type Receptors in Anterior Cingulate and Insula of Healthy Control Subjects but Not Methamphetamine-Dependent Individuals. [PDF]

open access: yes, 2015
BackgroundIndividuals with substance-use disorders exhibit emotional problems, including deficits in emotion recognition and processing, and this class of disorders also has been linked to deficits in dopaminergic markers in the brain.
Ghahremani, Dara G   +5 more
core   +2 more sources

Home - About - Disclaimer - Privacy