Results 211 to 220 of about 6,763,423 (338)

Role of Glutamate and NMDA Receptors in Alzheimer’s Disease

Journal of Alzheimer's Disease, 2016
Rui Wang, P. Reddy
semanticscholar   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Comparison of Micelles Single- and Dual-Targeted with Folic Acid and Biotin as the Delivery System of Docetaxel─The Influence of the Type and Amount of the Ligand on Morphology, Physicochemical Properties, and Cytotoxicity. [PDF]

Mol Pharm
Jurczyk M, Smolarczyk R, Musiał-Kulik M, Ciepła J, Matuszczak S, Cichoń T, Czapla J, Bochenek M, Foryś A, Wrześniok D, Beberok A, Jelonek K.   +11 more
europepmc   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Nuclear receptors in health and disease: signaling pathways, biological functions and pharmaceutical interventions. [PDF]

Signal Transduct Target Ther
Jin P, Duan X, Huang Z, Dong Y, Zhu J, Guo H, Tian H, Zou CG, Xie K.   +8 more
europepmc   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

The xylazine-fentanyl nexus: A public health emergency. [PDF]

SAGE Open Med
Sandhu KS, Kumar S, Garg K, Aggarwal K, Tiwwary M, Perry G, Bansal V, Jain R.   +7 more
europepmc   +1 more source

SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

British Journal of Pharmacology and Chemotherapy, 1997
O. Arunlakshana, Schild Ho
semanticscholar   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Absence of sex differences in serotonergic control of orbitofrontal cortex neuronal activity. [PDF]

Sci Rep
Mooney KM, Hoffman AF, Lupica CR.
europepmc   +1 more source