FEBS Open Bio, EarlyView.The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo +4 more
wiley +1 more source
Molecular Docking and Drug-Likeness of <i>Salicornia</i>-Derived Phytochemicals Against HER Receptors. [PDF]
Curr Issues Mol BiolWithana TN, Perera D, Fernando TD.
europepmc +1 more source
Functional parameters of spermatozoa obtained by a new selection device
FEBS Open Bio, EarlyView.This study compares density gradient centrifugation and the LensHooke CA0™ device for sperm separation. DGC requires multiple steps, specialized equipment, and technical expertise. In contrast, the CA0 device offers key practical and methodological advantages, resulting in a faster, simpler, and more affordable sperm selection method.
Julio C. Chávez +8 more
wiley +1 more source
Rhabdomyolysis After Risperidone Overdose in a Patient With Schizophrenia: A Case Report. [PDF]
Neuropsychopharmacol RepTakahashi J +5 more
europepmc +1 more source
Matrix: a complex amalgam of structures and functions in tumor microenvironment
FEBS Open Bio, EarlyView.The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis +3 more
wiley +1 more source
Structural insights into GPCR signaling activated by peptide ligands: from molecular mechanism to therapeutic application. [PDF]
Exp Mol MedKim J, Kim J, Choi C, Bae J, Choi HJ.
europepmc +1 more source
FEBS Open Bio, EarlyView.Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash +6 more
wiley +1 more source
Drug Exposure in Chronic Kidney Disease: It Is Not Just About the Glomerular Filtration Rate. [PDF]
Fundam Clin PharmacolLiabeuf S +6 more
europepmc +1 more source
Liver‐specific lncRNAs associated with liver cancers
FEBS Open Bio, EarlyView.Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina +3 more
wiley +1 more source
Cannabinoids and the endocannabinoid system in the regulation of cytochrome P450 metabolic activity-a review. [PDF]
Front PharmacolFonseca CDF, Zendulka O, Juřica J.
europepmc +1 more source