Results 131 to 140 of about 33,352 (233)

Endothelial Netrin‐4 regulates oligodendrocyte precursor cell proliferation and differentiation via ET‐1 signaling in preterm white matter injury

Brain Pathology, Volume 36, Issue 4, July 2026.
Our findings show early increased Netrin‐4 in mice with PWMI boosts angiogenesis and OPCs proliferation. Later, high levels hinder OPCs differentiation into mature cells, impairing myelination. It may act by stimulating ET‐1 secretion. Abstract Perinatal hypoxia–ischemia is a leading cause of preterm white matter injury (PWMI), yet mechanisms ...
Fuxing Dong, Weixing Yan, Qiqi Meng, Xueli Song, Bing Cheng, Yaping Liu, Yanan Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

Pharmacological treatment with a GABA(A) receptor modulator and a selective serotonin reuptake inhibitor as a mitigation strategy against aircraft noise‐induced cardiovascular and neuronal damage

British Journal of Pharmacology, Volume 183, Issue 13, Page 3762-3779, July 2026.
Abstract Background and Purpose Noise pollution, particularly by aircraft, is a significant risk factor for cardiovascular disease. Aircraft noise activates stress response pathways in the brain, via the amygdala, the sympathetic nervous system and the hypothalamic–pituitary–adrenal axis.
Ivana Kuntić, Marin Kuntić, Jiayin Zheng, Leonardo Nardi, Matthias Oelze, Arijan Valar, Dominika Mihaliková, Lea Strohm, Hans‐Georg Buchholz, Nicole Bausbacher, Simon Lange, Henning Ubbens, Qi Tang, Liyu Zhang, Guilherme Horta, Paul Stamm, Omar Hahad, Axel Methner, Sebastian Steven, Huige Li, Mathias Schreckenberger, Dilja Krueger‐Burg, Adrian Gericke, Michael J. Schmeisser, Thomas Münzel, Andreas Daiber   +25 more
wiley   +1 more source

5/6 Nephrectomy as an Experimental Model for Chronic Kidney Disease: New Vasoactive and Antioxidant Therapeutic Targets. [PDF]

Pharmaceuticals (Basel)
Aires RS, Correia Silva MDC, Barbosa FM, da Silva MC, Alves SML, Araújo AV, de Queiroz TM.   +6 more
europepmc   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, Volume 293, Issue 13, Page 3717-3757, July 2026.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Aprocitentan: An oral, once-daily antihypertensive therapy for resistant hypertension in adult patients. [PDF]

Heart Int
Valdes PO, Pickard B, Orakwue C, Ferdinand K.   +3 more
europepmc   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, Volume 293, Issue 13, Page 3899-3953, July 2026.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

Role of Mediterranean Diet Adherence on Endothelial Dysfunction in Autosomal Dominant Polycystic Kidney Disease Patients. [PDF]

Biomolecules
Salomone L, Menichelli D, Cammisotto V, Castellani V, Pastori D, Pignatelli P, Mitterhofer AP, Tinti F, Lai S.   +8 more
europepmc   +1 more source

Endothelin receptor [PDF]

Science-Business eXchange, 2008
openaire   +1 more source

In silico prioritisation of EDN1 missense variants identifies mature endothelin-1 substitutions with predicted receptor-binding effects. [PDF]

BMC Genomics
Sivakumar R, Arul Senghor KA, Vinodhini VM, Ramkumar KM.   +3 more
europepmc   +1 more source

The Involvement of Endothelin-1 in Sepsis and Organ Dysfunction-A Novel Biomarker in Patient Assessment. [PDF]

Biomedicines
Prepeliuc CS, Pasăre MA, Grigoriu MG, Miftode IL, Miftode RȘ, Vâță A, Costache-Enache II, Miftode EG.   +7 more
europepmc   +1 more source