Results 151 to 160 of about 577,108 (265)

Prevalence and Overlap of Malnutrition, Sarcopenia and Related Nutritional Syndromes in a Large Haemodialysis Population

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Chronic kidney disease is a major global health burden linked to malnutrition, sarcopenia and related nutritional syndromes including protein‐energy wasting (PEW)/cachexia and sarcopenic obesity (SO). Data from end‐stage kidney disease (ESKD) populations in Saudi Arabia and the wider Middle East are scarce.
Hanaa Noor, Subhashini Ganesan, Flavia Martinez Cantarutti, Ali Alharbi, Imed Helal, Joanne Reid, Adrian Slee   +6 more
wiley   +1 more source

GABA_{B} Receptors Regulate Chick Retinal Calcium Waves [PDF]

, 2001
Correlated spiking activity and associated Ca²⁺ waves in the developing retina are important in determining the connectivity of the visual system. Here, we show that GABA, via GABA_{B} receptors, regulates the temporal characteristics of Ca²⁺ waves ...
Catsicas, M, Mobbs, P
core  

Radiotherapy‐Induced Side Effects: Epidemiology, Pathogenesis, Prevention and Treatments

MedComm, Volume 7, Issue 10, October 2026.
Radiotherapy for malignancies frequently injures the organs’ systems through oxidative stress, fibrosis, inflammation, and vascular damage. This review systematically maps the epidemiology, pathogenesis, and emerging therapies to propose a mechanism‑network‑targeted framework for integrated, personalized care in radiation oncology.
Xiaowen Ma, Xiaoxuan Zhang, Pujun Zhao, Jiaxin Yang, Zhihao Li, Xiaoyang Han, Yixuan Wang, Zhenzhen Cui, Nian Liu, Min Li   +9 more
wiley   +1 more source

Evasins: Biology and Therapeutic Potential of Broad‐Spectrum Chemokine Inhibitors

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
ABSTRACT Ticks are haematophagous parasites that rely on uninterrupted bloodmeals for survival and need an effective strategy to suppress the host inflammatory response. Leukocyte recruitment is a chemokine‐mediated hallmark of inflammation, which ticks counteract via anti‐chemokine proteins in their saliva named evasins.
Emilia L. Bialek, Roos Buds, Ingrid Dijkgraaf, Pedro E. Marques   +3 more
wiley   +1 more source

Mechanisms of Thrombocytosis in Iron‐Deficiency Anemia

European Journal of Haematology, Volume 117, Issue 4, Page 728-738, October 2026.
ABSTRACT Iron‐deficiency anemia is frequently accompanied by reactive thrombocytosis, yet the mechanisms underlying this association remain incompletely understood. Beyond impaired erythropoiesis, iron availability has emerged as an active regulator of hematopoietic lineage decisions.
João Vitor Facco, Diane S. Krause, Sara T. Olalla Saad   +2 more
wiley   +1 more source

Pegcetacoplan Delivers Real‐World Therapeutic Benefits and Reduces Disease Burden for Patients With Paroxysmal Nocturnal Haemoglobinuria: A Systematic Literature Review of Pegcetacoplan Real‐World Clinical and Patient‐Reported Outcomes

European Journal of Haematology, Volume 117, Issue 4, Page 799-813, October 2026.
ABSTRACT Aims Paroxysmal nocturnal haemoglobinuria (PNH) is an ultra‐rare, acquired, non‐malignant haematological disorder that, if left untreated, can lead to significant morbidity. This systematic literature review (SLR) summarized real‐world evidence (RWE) for pegcetacoplan, a complement 3/3b inhibitor (C3i) available since 2021.
Juan Carlos Vallejo Llamas, Koo Wilson, Zalmai Hakimi, Vikte Lionikaite, Elisabetta Metafuni   +4 more
wiley   +1 more source

Altitude thresholds for hemoglobin and plasma volume regulation in adult residents of different altitudes and their impact on hemoglobin concentration

Physiological Reports, Volume 14, Issue 19, October 2026.
Abstract Life at altitude is characterized by increased erythropoietic activity and hemoglobin concentration ([Hb]). The first aim of the project was to identify the altitudes at which significant increases in hemoglobin mass (Hbmass) and decreases in plasma volume (PV) occur among residents living at different altitudes. The second aim was to evaluate
Edgar Cristancho‐Mejía, Andrea Catalina Trompetero‐Gonzalez, William Fernando Benavides‐Pinzón, Walter Franz‐Joachim Schmidt   +3 more
wiley   +1 more source

Joined Signatures of Erythropoietin and Interleukin-6 Signaling by Synthetic Heterodimeric gp130:Epo Receptor Complexes. [PDF]

ACS Synth Biol
Schlei J, Franke KF, Holzmann D, Wittich C, Floss DM, Rafii P, Brors K, Scheller J.   +7 more
europepmc   +1 more source

Erythropoietin and its lost receptor [PDF]

Nephrology Dialysis Transplantation, 2007
Alessio, Sturiale, Susanna, Campo, Eleonora, Crascì, Giuseppe, Coppolino, Davide, Bolignano, Giovanni, Grasso, Michele, Buemi   +6 more
openaire   +2 more sources

Low Carbohydrate Availability in Energy Balance Alters Bone Turnover and Muscle Proteomic Response With Limited Endocrine Disruption

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Eight trained males completed 4 days of normal‐carbohydrate or low‐carbohydrate (81% reduction in carbohydrate) diets while maintaining energy balance and undertaking daily exercise. Low carbohydrate decreased total body water and fat‐free mass, increased circulating free fatty acids, glycerol and β‐hydroxybutyrate, alongside increased fat oxidation at
Erick Mosquera‐Lopez, Harry L. Taylor, Yusuke Nishimura, Carl Langan‐Evans, Sam O. Shepherd, Juliette A. Strauss, James P. Morton, Jatin G. Burniston, Jose L. Areta   +8 more
wiley   +1 more source