Results 131 to 140 of about 19,757 (238)

Statistical Discrimination of Urinary Steroid Biomarkers in the Athlete Biological Passport: A Novel Approach to an Abnormal Steroid Profile Score (ASPS)

Drug Testing and Analysis, Volume 18, Issue 5, Page 608-618, May 2026.
The study developed a single Abnormal Steroid Profile Score (ASPS) to improve interpretation of the Athlete Biological Passport steroid module. Using Bayesian modelling and logistic regression, biomarker patterns from laboratory and doping control data successfully discriminated between doped and clean individuals, with improved classification ...
James G. Hopker, Jim E. Griffin, Matthew N. Fedoruk, Laura A. Lewis   +3 more
wiley   +1 more source

Erythropoietin receptor upregulation is associated with tubular injury severity in human acute kidney injury. [PDF]

Ren Fail
Xie K, Zhou G, Li M, Fu L, Wang R, Zhang L, Mei C, Xue C, Xu D.   +8 more
europepmc   +1 more source

CDK6 inactivation counteracts CALR‐mutant‐induced MPN evolution and sensitizes MPN stem cells to interferon‐α treatment

HemaSphere, Volume 10, Issue 5, May 2026.
Abstract Interferon‐α (IFNα) remains a potent therapeutic option for myeloproliferative neoplasms (MPNs) with an activated JAK/STAT signaling axis. However, variable patient responses highlight the need for optimized combination strategies. Recent studies suggest a link between cyclin‐dependent kinase 6 (CDK6) and IFN signaling.
Brian Ringhofer, Wolfram Polzer, Michaela Prchal‐Murphy, Eszter Doma, Sebastian Kollmann, Elisabeth Gamper, Jonatan Kendler, Belinda S. Maw, Eva Zebedin‐Brandl, Juan Li, Anthony R. Green, Maria‐Theresa Krauth, Emir Hadzijusufovic, Daniel Ivanov, Peter Valent, Gregor Hoermann, Thorsten Klampfl, Veronika Sexl, Karoline Kollmann   +18 more
wiley   +1 more source

UBE2O as a key regulator of drug-induced erythropoiesis in the context of myelodysplastic syndromes. [PDF]

Blood Adv
Maffeo B, Panuzzo C, Savi A, Itri F, Piccioli S, Danzero AC, Maglione A, Marini S, Voso MT, Fava C, Bracco E, Pergolizzi B, Cilloni D.   +12 more
europepmc   +1 more source

Diagnostic and Therapeutic Roles of Extracellular Vesicles in Chronic Kidney Disease: A Systematic Review

Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
This systematic review compiles and analyses 364 studies on chronic kidney disease (CKD) that investigated extracellular vesicles (EVs) for diagnostic and therapeutic applications. By systematically categorizing data according to EV source and cargo, it provides an integrated overview of EV application for CKD, highlighting common approaches and shared
Tunahan Ergunay, Alessia Brossa, Benedetta Bussolati   +2 more
wiley   +1 more source

Research progress on the intrinsic link between the occurrence and progression of malignant tumors, chronic kidney disease and drug safety. [PDF]

Am J Cancer Res
Zhang D, Jiang S, Liu L, Lu J, Li W.
europepmc   +1 more source

Plasma Dilution After Myocardial Ischemia–Reperfusion Injury Promotes Cardiac Repair, Heart Performance, and Recovery of Motor Function and Endurance in Old Mice

Aging Cell, Volume 25, Issue 5, May 2026.
Plasma dilution at 24 h after I/R improved cardiac remodeling, function, and the physical performance of old male and female mice, through lowered markers of inflammation, fibrosis, reduction of cardiomyocytes' apoptosis, increase in their cell‐cycle re‐entry, and healthier profile of newly synthesized proteome, including the determinants of Jak/Stat ...
Joana Marie C. Cruz, Rana Alzalzalee, Hayden Yeung, Zainab Mahmood, Qile Yang, Negar Morshedian, Zachery R. Robinson, Karan R. Malhotra, Michael J. Conboy, Ahmad Reza Mazahery, Jose B. Nevado, Irina M. Conboy   +11 more
wiley   +1 more source

Specialty grand challenge: existing issues and emerging frontiers in renal endocrinology. [PDF]

Front Endocrinol (Lausanne)
Haque ATME, Razzaque MS.
europepmc   +1 more source

Neural Correlates of Cognitive Improvement After Virtual Reality‐Based Cognitive Remediation in Psychosis and Mood Disorders: A Randomized Controlled Trial

Acta Psychiatrica Scandinavica, Volume 153, Issue 5, Page 553-562, May 2026.
ABSTRACT Introduction Cognitive impairment in mood disorders and schizophrenia spectrum disorders hampers patients' clinical and functional outcomes. A key challenge in pro‐cognitive treatment development is the limited insight into the underlying neurocircuitry correlates of cognitive changes.
Viktoria Damgaard, Andreas Elleby Jespersen, Ida Kruse Søndergaard, Anders Lumbye, Maj Vinberg, Louise Birkedal Glenthøj, Merete Nordentoft, Anjali Sankar, Gitte Moos Knudsen, Julian Macoveanu, Kamilla Woznica Miskowiak   +10 more
wiley   +1 more source

When two signals are better than one: Synergistic control of erythropoiesis. [PDF]

PLoS Biol
Wilson NK.
europepmc   +1 more source