Results 221 to 230 of about 127,469 (270)

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Central Serous Chorioretinopathy in Endometriosis Treatment with Progestogen: A Metabolic Understanding. [PDF]

Life (Basel)
Chiara F, Allegra S, Caudana M, Mula J, Turco D, Liuzzi S, Puccinelli MP, Mengozzi G, De Francia S.   +8 more
europepmc   +1 more source

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

Correction: Placental expression of estrogen and progesterone receptors and vascular endothelial growth factor in buffaloes suffering from uterine torsion. [PDF]

BMC Vet Res
Amin YA, Elnegiry AA, Awadalla EA, Hussein HA, Mohamed RH.   +4 more
europepmc   +1 more source

A possible important regulatory role of estrogen in obstructive sleep apnea hypoventilation syndrome. [PDF]

Front Med (Lausanne)
Zhou P, Li H, Li H, Chen Y, Lv Y.
europepmc   +1 more source

Effects of perampanel on bone health in adult patients with epilepsy

Epilepsia Open, EarlyView.
Abstract Objective The objective was to assess the effects of perampanel (PER) on bone metabolism and bone mineral density (BMD) in adult patients with epilepsy. Methods This retrospective study included consecutive patients admitted to the Epilepsy Center of Sichuan Provincial People's Hospital from January 2023 to June 2024.
Mingxing Yu, Nana Zhang, Chunyan Chen, Yuxuan He, Jing Meng, Wen Luo, Yi Liang, Yi Guo, Liang Yu   +8 more
wiley   +1 more source

Interaction of GPER-1 with the endocrine signaling axis in breast cancer. [PDF]

Front Endocrinol (Lausanne)
Molina Calistro L, Arancibia Y, Olivera MA, Domke S, Torres RF.   +4 more
europepmc   +1 more source

Oxytocin Amplifies Negative Response to Ambiguity in Adolescent Females With and Without Eating Disorders

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Eating disorders (ED) typically emerge in adolescence, a critical period for brain development and peer bonding. Interpersonal difficulties—particularly social anxiety—frequently co‐occur with ED. Oxytocin is a neuropeptide that modulates social cognition and linked to prosocial effects.
Victoria Burmester, Emerie Sheridan, Nikita Catalina Julius, Jordan Elliott, Olivia Thackeray, Dasha Nicholls   +5 more
wiley   +1 more source

Perimenopausal depression: Targeting inflammation and oxidative stress (Review). [PDF]

Mol Med Rep
Yu Y, Yu T, Liu K, Li Y, Luan Y, Yang T, Li W, Cong H, Wu X.   +8 more
europepmc   +1 more source

Comparing Transcriptomic Responses to Chemicals Across Six Species Using the EcoToxChip RNASeq Database

Environmental Toxicology and Chemistry, EarlyView.
Abstract The EcoToxChip project includes RNA‐sequencing data from experiments involving model (Japanese quail, fathead minnow, African clawed frog) and ecological (double‐crested cormorant, rainbow trout, northern leopard frog) species at multiple life stages (whole embryo and adult) exposed to eight chemicals of environmental concern known to perturb ...
Krittika Mittal, Jessica Ewald, Doug Crump, Jessica Head, Markus Hecker, Natacha Hogan, Jianguo Xia, Niladri Basu   +7 more
wiley   +1 more source