Results 231 to 240 of about 262,647 (304)

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

Environmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz, Melanie Blanc‐Legendre, Maximilian Rinderknecht, Laura Behnstedt, Sara Coordes, Luisa Reger, Sacha Sire, Xavier Cousin, Thomas Braunbeck, Lisa Baumann   +9 more
wiley   +1 more source

Human Cancers Derived from Either Genetic or Lifestyle Factors Are Initiated by Impaired Estrogen Signaling. [PDF]

Cancers (Basel)
Suba Z.
europepmc   +1 more source

Unraveling TIME: CD8+ T cell- and CXCL11-driven endocrine resistance in breast cancer. [PDF]

J Clin Invest
Kong T, Ma CX.
europepmc   +1 more source

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

Introducing a New Hypothesis in the Genesis of Breast Cancer: An Integrative Review. [PDF]

Breast Cancer (Dove Med Press)
Andrade Pachnicki JP, Cayet CM, Dos Santos DAH, Junkes GB, Petry J, Hibarino MEM, Lodi Carvalho VL.   +6 more
europepmc   +1 more source

Evaluation of the effect of flaxseed oil and docosahexaenoic acid on hematological and oxidative stress markers of female Wistar rats with 7, 12‐dimethylbenz[a]anthracene‐induced breast cancer

Food Biomacromolecules, EarlyView.
DHA and flaxseed oil reduce tumor sizes, superoxide dismutase activity, malondialdehyde level and increase white blood cells, platelets, serum protein level, glutathione peroxidase, nitric oxide, catalase activities in DMBA‐induced breast cancer in Wistar rats compared to the negative control.
Julia Ndifor Mebami, Achidi Aduni Ufuan, Ines Sorelle Fotsing, Sab Sharon Mbape, Fabrice Tonfack Djikeng, Stephane Zingue   +5 more
wiley   +1 more source

Disruption of estrogen signaling by developmental exposure to BPA and TBT causes long term functional deficits in zebrafish retina. [PDF]

Front Pharmacol
Jensen JS, Ouellette L, Harris R, Owrang P, Connaughton VP.   +4 more
europepmc   +1 more source

Recent Perspectives on Phytochemical Profile, Pharmacological Activities, and Industrial Applications of Guava (Psidium guajava)

Food Safety and Health, EarlyView.
Psidium guajava leaves contain potent bioactive compounds like quercetin, myricetin, and triterpenoids that show antioxidant, antidiabetic, anti‐inflammatory, and anticancer effects. They act by modulating NF‐κB, PPARγ, and α‐glucosidase and by inducing apoptosis and cell cycle arrest.
Muhammad Waqar, Sehrish Jabbar, Qudrat Ullah, Farhang Hameed Awlqadr, Muhammad Tayyab Arshad, Md. Sakhawot Hossain, Sammra Maqsood, Ali Ikram, Ammar Ahmad Khan, Worawan Panpipat, Manat Chaijan   +10 more
wiley   +1 more source

Phytochemicals and Health Benefits of American Ginseng (Panax quinquefolius L.): Current Knowledge and Future Perspectives

Food Safety and Health, EarlyView.
This review summarizes the chemical constituents and functional characteristics of American ginseng, aiming to provide references for its development and application. ABSTRACT American ginseng, a perennial herbaceous plant, is recognized for its significant medicinal properties and has attracted considerable attention due to its diverse phytochemical ...
Wei Geng, Ning Zhou, Jinqian Yu, Yanling Geng, Xiao Wang, Yannan Chen   +5 more
wiley   +1 more source

Association of Chronic Diseases With Herpes Zoster in China: A Nationwide Population‐Based Survey

Health Care Science, EarlyView.
Chronic disease was associated with elevated herpes zoster risk (aOR = 1.84, 95% CI: 1.51–2.24). Among 14 chronic conditions, heart disease showed the strongest association (aOR = 2.91, 95% CI: 2.07–4.10), followed by diabetes (aOR = 2.04, 95% CI: 1.48–2.80) and hypertension (aOR = 1.89, 95% CI: 1.47–2.42).
Wenhui Zhu, Yiqi Xia, Yanran Wang, Zhenyu Shi, Yang Shen, Chengsen Cui, Jinxu Ai, Yemin Yuan, Xin Ye, Dawei Zhu, Ping He   +10 more
wiley   +1 more source