Results 221 to 230 of about 785,146 (253)

Cardiovascular toxicity induced by TKIs in patients with chronic myeloid leukaemia: Are women and men different?

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.
This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo   +10 more
wiley   +1 more source

Selective N‐Functionalization of Pyrazoles

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
This review traces the evolution of regioselective N‐functionalization strategies for pyrazoles, a key class of nitrogen heterocycles widely used in medicinal chemistry. Due to rapid tautomerism, N‐functionalization often lacks selectivity, leading to poor and unpredictable regioisomeric outcomes.
Lucas Popek   +2 more
wiley   +1 more source

Short-term vaginal prasterone therapy induces steroid receptor modulation and extracellular matrix remodeling in human vaginal mucosa. [PDF]

open access: yesSci Rep
Tomczyk K   +8 more
europepmc   +1 more source

The effect of antiseizure medications on the exposure to combined oral contraceptives: A systematic review and network meta‐analysis

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Current recommendations for prescribing combined oral contraceptives (COCs) to people with epilepsy are often conflicting, particularly for weak inducers of cytochrome P450 3A4. We aimed to critically review the literature and compare the antiseizure medication (ASM)‐induced changes in exposure to COC components.
Hagar Cohen   +4 more
wiley   +1 more source

Menopause and skin. [PDF]

open access: yesMenopause
Wentworth A.
europepmc   +1 more source

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