Results 231 to 240 of about 2,636,320 (328)

Development of Carborane‐Based Halogenated Naphthyridinone‐Analogues as Cannabinoid Receptor Type 2 (CB2R) Ligands

open access: yesChemMedChem, EarlyView.
There is no suitable radioligand for positron emission tomography imaging of CB2R overexpression for routine clinical usage. Herein, the synthesis, characterization, binding affinity, and docking studies of carborane‐based halo‐substituted naphthyridinone derivatives as CB2R ligands are presented.
Lea Ueberham   +4 more
wiley   +1 more source

Highly Sensitive, Low‐Cost Deep‐UV Resonant Raman Microspectroscopy Systems

open access: yesChemistry–Methods, EarlyView.
Low‐cost deep UV resonant Raman microscope for chemical sensing and imaging has been developed and its performance has been experimentally validated for several potential applications. Multimodal imaging capabilities of a new instrument have been demonstrated as well.
Joseph Harrington   +5 more
wiley   +1 more source

Single-cell RNA sequencing reveals the potential role of estrogen in tuberous sclerosis complex related renal angiomyolipoma. [PDF]

open access: yesDiscov Oncol
Liu Y   +10 more
europepmc   +1 more source

Estrogen receptors and the metabolic network.

open access: yesCell Metabolism, 2011
R. Barros, J. Gustafsson
semanticscholar   +1 more source

Pharmacokinetics, Safety, and Skin Irritation and Sensitization Potential of Clascoterone Cream in Early‐Phase Clinical Study Participants

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Clascoterone is an androgen receptor inhibitor approved for the treatment of acne vulgaris in patients 12 years of age and older. Here, we report results of 5 phase 1 studies that assessed the pharmacokinetics (PK), safety, and skin irritation and sensitization potential of clascoterone cream 1% in healthy participants and patients with acne ...
Andrea Francesco Daniele Di Stefano   +8 more
wiley   +1 more source

Mini review: Bidirectional Regulation of Circadian Rhythm by Suprachiasmatic Nucleus and Nuclear Receptors in Female Mammals. [PDF]

open access: yesJ Circadian Rhythms
Shanmugam DAS   +11 more
europepmc   +1 more source

Deciphering the transcriptomic landscape of early HR+/HER2− breast cancer in very young women

open access: yes
Cancer Communications, EarlyView.
Iris Garrido‐Cano   +15 more
wiley   +1 more source

Disposition and Absolute Bioavailability of Oral Imlunestrant in Healthy Women: A Phase 1, Open‐Label Study

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Imlunestrant (LY3484356) is a next‐generation orally bioavailable selective estrogen receptor degrader being investigated for the treatment of estrogen receptor–positive advanced breast and endometrial cancers. This Phase 1, open‐label, 2‐part study evaluated the disposition and absolute bioavailability of [14C]‐imlunestrant in 16 US‐based ...
Amita Datta‐Mannan   +6 more
wiley   +1 more source

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