Results 231 to 240 of about 258,016 (314)

Effect of vepdegestrant, a PROTAC oestrogen receptor degrader, on dabigatran and rosuvastatin pharmacokinetics in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims To evaluate the effects of vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) oestrogen receptor degrader, on the pharmacokinetics of dabigatran (a P‐glycoprotein [P‐gp] substrate) and rosuvastatin (a breast cancer resistance protein [BCRP] substrate).
Derek Z. Yang, Li Zhou, Jennifer A. Winton, Kyle T. Matschke, Constantino Kantaridis, Kristine Doyle, Kimberly C. Lee, Naihan Chen, Yuanyuan Zhang, Weiwei Tan   +9 more
wiley   +1 more source

The role of dysbiosis in shaping host immunity in endometrial cancer development. [PDF]

Front Immunol
Wierzbińska W, Kuźmycz O, Kowalczyk A, Stączek P.   +3 more
europepmc   +1 more source

Endometrial cancer: from clinical reality to molecular treatment. [PDF]

Discov Oncol
Renaud LI, St-Laurent E, Compare C, Proulx R, Nolan J, Asselin E.   +5 more
europepmc   +1 more source

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

BMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah, Xingxing Li, Hao Yuan, Huiling Shen, Shaohao Quan, Guifang Pan, Muhammad Ishfaq, Abid Ullah Shah, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source

Sustainable Meat Consumption: Values, Drivers, and Barriers—A Mixed‐Method Study With Post hoc Qualitative Analysis

Business Strategy and the Environment, EarlyView.
ABSTRACT Growing health and environmental concerns associated with traditional meat production and consumption drive the commercialization of sustainable meats (SMs) as a viable alternative. The greatest challenge to feed the growing population can be addressed with SMs that are produced, consumed, and disposed of in a manner that protects our ...
Munish Saini, Gyan Prakash, Reeti Agarwal, Rsha Alghafes, Laura Broccardo   +4 more
wiley   +1 more source

New Perspectives on the Use of Resveratrol in the Treatment of Metabolic and Estrogen-Dependent Conditions Through Hormonal Modulation and Anti-Inflammatory Effects. [PDF]

Curr Issues Mol Biol
Renke G, Fuschini AC, Clivati B, Teixeira LM, Cuyabano ML, Erel CT, Rosado EL.   +6 more
europepmc   +1 more source

The Development of the Human Female Reproductive Tract. Part 1: Uterine Tube and Uterus

Clinical Anatomy, EarlyView.
ABSTRACT The uterine tubes and uterus develop from the paramesonephric (Müllerian) ducts. Most experimental data are obtained in rodents. Since the (micro‐)anatomy of the murine urogenital tract differs from that in humans, evaluation of the translatability of mouse data to human development is relevant.
Cindy J. M. Hülsman, S. Eleonore Köhler, Gabriela Morosan‐Puopolo, Jill P. J. M. Hikspoors, Wouter H. Lamers   +4 more
wiley   +1 more source

Polycyclic Aromatic Hydrocarbons in Marine Environments Affect Fish Reproduction-A Critical Review. [PDF]

Toxics
Pozzan R, de Almeida Roque A, Iwamoto H, de Campos Guerreiro F, da Silva AP, Rubio-Vargas DA, de Marchi M, de Oliveira F, Martínez-Burgos WJ, Prodocimo MM, de Oliveira Ribeiro CA.   +10 more
europepmc   +1 more source

Examining Gender and Cultural Influences on Customer Emotions

Journal of Consumer Behaviour, EarlyView.
ABSTRACT Understanding consumer emotional experiences on e‐commerce platforms is crucial for businesses seeking to enhance customer engagement and personalization. Recent research has demonstrated that these experiences are more intricate and diverse than previously examined, encompassing a wider range of discrete emotions and spanning multiple ...
Vinh Truong
wiley   +1 more source