Results 111 to 120 of about 134,430 (166)

Effects of Ox-LDL on Macrophages NAD(P)H Autofluorescence Changes by Two-photon Microscopy [PDF]

, 2006
Ox-LDL uptakes by macrophage play a critical role in the happening of atherosclerosis. Because of its low damage on observed cells and better signal-to- background ratio, two-photon excitation fluorescence microscopy is used to observe NAD(P)H ...
Dong, Chen-Yuan, Lee, Szu-Yuan, Lin, Chii-Wann, Lin, Ching-Ting, Lu, Long-Sheng, Tien, En-Kuang, Wu, Chau-Chung   +6 more
core   +1 more source

Metastatic Tumor Cells Exploit Their Adhesion Repertoire to Counteract Shear Forces during Intravascular Arrest

Cell Reports, 2019
Summary: Cancer metastasis is a process whereby a primary tumor spreads to distant organs. We have demonstrated previously that blood flow controls the intravascular arrest of circulating tumor cells (CTCs) through stable adhesion to endothelial cells ...
Naël Osmani, Gautier Follain, María J. García León, Olivier Lefebvre, Ignacio Busnelli, Annabel Larnicol, Sébastien Harlepp, Jacky G. Goetz   +7 more
doaj  

Binding Selectivity Analysis from Alchemical Receptor Hopping and Swapping Free Energy Calculations [PDF]

arXiv
We present receptor hopping and receptor swapping free energy estimation protocols based on the Alchemical Transfer Method (ATM) to model the binding selectivity of a set of ligands to two arbitrary receptors. The receptor hopping protocol, where a ligand is alchemically transferred from one receptor to another in one simulation, directly yields the ...
arxiv  

Characterization of Domeless receptors and the role of BdDomeless3 in anti-symbiont-like virus defense in Bactrocera dorsalis

Journal of Integrative Agriculture
The Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling pathway play a pivotal role in innate immunity. Among invertebrates, Domeless receptors serve as the key upstream regulators of this pathway.
Wei Zhang, Shaoyang Li, Rong Li, Jinzhi Niu, Jinjun Wang   +4 more
doaj  

Regulation of Rho Family GTPases by Cell-Cell and Cell-Matrix Adhesion

Biological Research, 2002
Integrins and cadherins are transmembrane adhesion receptors that are necessary for cells to interact with the extracellular matrix or adjacent cells, respectively.
WILLIAM T. ARTHUR, NICOLE K. NOREN, KEITH BURRIDGE   +2 more
doaj  

A proteomics approach to isolating neuropilin-dependent α5 integrin trafficking pathways: neuropilin 1 and 2 co-traffic α5 integrin through endosomal p120RasGAP to promote polarised fibronectin fibrillogenesis in endothelial cells

Communications Biology
Integrin trafficking to and from membrane adhesions is a crucial mechanism that dictates many aspects of a cell’s behaviour, including motility, polarisation, and invasion. In endothelial cells (ECs), the intracellular traffic of α5 integrin is regulated
Christopher J. Benwell, Robert T. Johnson, James A. G. E. Taylor, Jordi Lambert, Stephen D. Robinson   +4 more
doaj   +1 more source

Extracellular vesicles adhere to cells primarily by interactions of integrins and GM1 with laminin. [PDF]

J Cell Biol
Isogai T, Hirosawa KM, Kanno M, Sho A, Kasai RS, Komura N, Ando H, Furukawa K, Ohmi Y, Furukawa K, Yokota Y, Suzuki KGN.   +11 more
europepmc   +1 more source

Hidden pathway: the role of extracellular matrix in type 2 diabetes mellitus-related sarcopenia. [PDF]

Front Endocrinol (Lausanne)
Sun Y, Zhang Z, Wang Y, Wu X, Sun Y, Lou H, Xu J, Yao J, Cong D.   +8 more
europepmc   +1 more source

Mechanical forces in the tumor microenvironment: roles, pathways, and therapeutic approaches. [PDF]

J Transl Med
Zhang Y, Fu Q, Sun W, Yue Q, He P, Niu D, Zhang M.   +6 more
europepmc   +1 more source

Structural basis of aggregative adherence fimbriae II interactions with sialic acid, mucin, and human intestinal cells. [PDF]

Infect Immun
Hagin LW, Mandomando I, Ruiz-Perez F, Wright NT, Gonyar LA.   +4 more
europepmc   +1 more source