Results 261 to 270 of about 151,588 (287)
Some of the next articles are maybe not open access.
Changes in cell surface expression of fibronectin and fibronectin receptor during liver regeneration
Journal of Cell Science, 1992ABSTRACT The surface expression of fibronectin and its major integrin receptor in liver, integrinα5β1 was studied during liver regeneration after partial hepatectomy. Using immunoblotting, plasma membranes isolated from livers at different regeneration stages were found to contain 6- to 8-fold elevated levels of fibronectin, α5 and β1 at
C, Pujades +3 more
openaire +2 more sources
Fibronectin Receptor Expression on Thymocytes
1990Entrance of precursor T cells into the thymus and their subsequent exit into the circulation are prerequisite events for development of mature T-lymphocyte characteristics (1). Thymic epithelial cells may play an integral role in thymocyte differentiation, both through direct contact and by secretion of thymic hormones (2).
Michael D. Pierschbacher +1 more
openaire +1 more source
Interaction of fibronectin with its receptor on platelets
Cell, 1985We report that the 12,000 dalton domain of fibronectin that interacts with fibroblast cell surfaces also binds specifically to thrombin-inducible, saturable receptors on platelets. Furthermore, we have used chemical cross-linking and monoclonal antibodies to show that the 12,000 dalton domain of fibronectin interacts directly with glycoprotein IIIa at ...
Gardner, J M, Hynes, R O
openaire +2 more sources
Effect of selenite on cell surface fibronectin receptor
Biological Trace Element Research, 1994Incubation of cells with selenite, under conditions in which there is no effect on cell viability, results in a decrease in the rate of their subsequent attachment to extracellular matrix proteins such as fibronectin (1). The attachment was inhibited by a pentapeptide containing the RGD sequence and by antibody against the cellular fibronectin receptor
L, Yan, G D, Frenkel
openaire +2 more sources
BHK cell variant with defective fibronectin receptor function
Cell Biology International Reports, 1984Baby hamster kidney cells were mutagenized with N-methyl-N'-nitro-N-nitrosoguanidine and selected to obtain a population of non-attaching cells. The cell variant FN-1 was cloned from the non-attaching cell population, recloned, and tested for cell adhesive interactions using four different assays of fibronectin (pFN) receptor function: cell attachment ...
N, Oppenheimer-Marks +2 more
openaire +2 more sources
Experimental Cell Research, 1989
From a collection of more than 80 nonoverlapping clones, isolated by differential screening of a lambda cDNA library prepared from serum-stimulated cells in the presence of cycloheximide, we have identified four clones that encoded for components of the cytoskeleton and extracellular matrix.
R P, Ryseck +3 more
openaire +2 more sources
From a collection of more than 80 nonoverlapping clones, isolated by differential screening of a lambda cDNA library prepared from serum-stimulated cells in the presence of cycloheximide, we have identified four clones that encoded for components of the cytoskeleton and extracellular matrix.
R P, Ryseck +3 more
openaire +2 more sources
Regulation of fibronectin receptor distribution.
The Journal of cell biology, 1992To determine the role of each intracellular domain of the fibronectin receptor in receptor distribution, chimeric receptors were constructed containing the human interleukin-2 receptor (gp55 subunit) as the extracellular and transmembrane domains, in combination with either the alpha 5 or beta 1 intracellular domain of the fibronectin receptor as the ...
S E, LaFlamme, S K, Akiyama, K M, Yamada
openaire +1 more source
Experimental Cell Research, 1988
We have used a rat neural cell line, B65, to investigate the relative contributions of gangliosides and glycoprotein receptors in adhesion to fibronectin. Monoclonal antibodies against two neuroectoderm-associated gangliosides, D1.1 and GD3, inhibit the rate of B65 attachment to fibronectin, suggesting that these gangliosides are involved in the ...
openaire +2 more sources
We have used a rat neural cell line, B65, to investigate the relative contributions of gangliosides and glycoprotein receptors in adhesion to fibronectin. Monoclonal antibodies against two neuroectoderm-associated gangliosides, D1.1 and GD3, inhibit the rate of B65 attachment to fibronectin, suggesting that these gangliosides are involved in the ...
openaire +2 more sources
Fibronectin and Its Integrin Receptors in Cancer
1999The adhesive extracellular matrix protein fibronectin and its integrin receptors play important roles at several stages of tumor development. Tumor cells are generally less adhesive than normal cells and deposit less extracellular matrix. The loosened matrix adhesion that results may contribute to the ability of tumor cells to leave their original ...
openaire +2 more sources
Fibronectins and Their Receptors in Cancer
2009The extracellular matrix protein fibronectin and its receptors (integrins α5β1, α4β1, α9β1, αvβ3, αvβ1, and αvβ6) play an active role in tumor growth and metastasis. Numerous tumors exhibit increased expression of fibronectin and its receptors, thereby promoting proliferation, survival, and motility of tumor cells as well as their subsequent metastasis.
Christie J. Avraamides, Judith A. Varner
openaire +1 more source