Identification of novel adhesins of M. tuberculosis H37Rv using integrated approach of multiple computational algorithms and experimental analysis. [PDF]
PLoS ONE, 2013 Pathogenic bacteria interacting with eukaryotic host express adhesins on their surface. These adhesins aid in bacterial attachment to the host cell receptors during colonization.
Sanjiv Kumar +4 more
doaj +1 more source
Cranial and trunk neural crest cells use different mechanisms for attachment to extracellular matrices [PDF]
, 1992 We have used a quantitative cell attachment assay to compare the interactions of cranial and trunk neural crest cells with the extracellular matrix (ECM) molecules fibronectin, laminin and collagen types I and IV.
Artinger, Kristin B. +3 more
core
Downregulation of TGF-β Receptor-2 Expression and Signaling through Inhibition of Na/K-ATPase. [PDF]
PLoS ONE, 2016 Transforming growth factor-beta (TGF-β) is a multi-functional cytokine implicated in the control of cell growth and differentiation. TGF-β signals through a complex of TGF-β receptors 1 and 2 (TGFβR1 and TGFβR2) that phosphorylate and activate Smad2/3 ...
Jennifer La +7 more
doaj +1 more source
Cell migration within confined sandwich-like nanoenvironments [PDF]
, 2015 Aim: We introduced sandwich-like cultures to provide cell migration studies with 4 representative nano-bio-environments where both ventral and dorsal cell receptors are activated.
Ballester-Beltrán, José +3 more
core +1 more source
Modeling Tumor Angiogenesis with Cellular Automata [PDF]
arXiv, 2019 Angiogenesis is the formation of new blood vessels from the existing vessels. During tumour angiogenesis, tumour cells secret a number of chemical substrates called tumour angiogenic factors (TAFs). These factors diffuse through the extracellular matrix (ECM) and degrade the basement membrane of nearby vasculature.
arxiv
Pseudomonas aeruginosa adhesion to normal and injured respiratory mucosa
Memorias do Instituto Oswaldo Cruz, 1992 Human nasal polyps outgrowth culture were used to study the adhesion of Pseudomonas aeruginosa to respiratory cells. By transmission electron microscopy, bacteria associated with ciliated cells were identified trapped at the extremities of cilia, usually
M. C. Plotkowski +3 more
doaj +1 more source
Novel Role of Src in Priming Pyk2 Phosphorylation. [PDF]
PLoS ONE, 2016 Proline-rich tyrosine kinase 2 (Pyk2) is a member of the focal adhesion kinase (FAK) family of non-receptor tyrosine kinases and plays an important role in diverse cellular events downstream of the integrin-family of receptors, including cell migration ...
Ming Zhao +3 more
doaj +1 more source
Vitronectin as a micromanager of cell response in material-driven fibronectin nanonetworks [PDF]
, 2017 Surface functionalization strategies of synthetic materials for regenerative medicine applications comprise the development of microenvironments that recapitulate the physical and biochemical cues of physiological extracellular matrices. In this context,
Altankov +66 more
core +1 more source
Vulnerability of geriatric patients to biomaterial associated infections: in vitro study of biofilm formation by Pseudomonas aeruginosa on orthopedic implants [PDF]
arXiv, 2015 Fibronectin, a glycoprotein secreted by connective tissue cells is found in the human plasma as well as in the ECM. It is known to have an adhesive property and plays a role in cell-to-cell and cell-to-substratum adhesions. In rheumatoid arthritis (RA) and osteoarthritis (OA), fibronectin is locally synthesized by the synovial cells, and the synovial ...
arxiv
Distinct functions of integrin alpha and beta subunit cytoplasmic domains in cell spreading and formation of focal adhesions. [PDF]
, 1993 Integrin-mediated cell adhesion often results in cell spreading and the formation of focal adhesions. We exploited the capacity of recombinant human alpha IIb beta 3 integrin to endow heterologous cells with the ability to adhere and spread on fibrinogen
Chen, Y +5 more
core