Results 191 to 200 of about 18,956 (224)

N-Formylated humanin activates both formyl peptide receptor-like 1 and 2

Biochemical and Biophysical Research Communications, 2004
We have discovered that humanin (HN) acts as a ligand for formyl peptide receptor-like 1 (FPRL1) and 2 (FPRL2). This discovery was based on our finding that HN suppressed forskolin-induced cAMP production in Chinese hamster ovary (CHO) cells expressing human FPRL1 (CHO-hFPRL1) or human FPRL2 (CHO-hFPRL2). In addition, we found that N-formylated HN (fHN)
Masataka, Harada, Yugo, Habata, Masaki, Hosoya, Kazunori, Nishi, Ryo, Fujii, Makoto, Kobayashi, Shuji, Hinuma   +6 more
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Formyl Peptide Chemotactic Receptors of Leukocytes and Macrophages

1980
Publisher Summary Polymorphonuclear leukocytes, monocytes, and macrophages play a central role in host defence against invading microorganisms. However, the killing mechanisms employed by these motile cells are effective over short distances and require intimate cell-microorganism contact. A mechanism for ensuring efficient accumulation of phagocytic
J E, Niedel, P, Cuatrecasas
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Vomeronasal Formyl Peptide Receptors in mammals

2016
This thesis uncovers the genetic accidents that led to the acquisition of Formyl Peptide Receptor gene expression in the vomeronasal system of a rodent lineage that represents about 23% of the mammalian species. We also examined whether the cluster organization of vomeronasal genes is involved in the regulation of their expression with the presence of ...
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Mitochondrial N-formyl peptides cause airway contraction and lung neutrophil infiltration via formyl peptide receptor activation

Pulmonary Pharmacology & Therapeutics, 2016
Respiratory failure is a common characteristic of systemic inflammatory response syndrome (SIRS) and sepsis. Trauma and severe blood loss cause the release of endogenous molecules known as damage-associated molecular patterns (DAMPs). Mitochondrial N-formyl peptides (F-MITs) are DAMPs that share similarities with bacterial N-formylated peptides, and ...
Camilla Ferreira Wenceslau, Theodora Szasz, Cameron G. McCarthy, Babak Baban, Elizabeth NeSmith, R. Clinton Webb   +5 more
openaire   +2 more sources

The Formyl Peptide Chemotactic Receptor: Cellular Processing of Peptide and Receptor

1983
An integrated series of complex cellular functions of polymorphonuclear leukocytes, monocytes and macrophages comprise the inflammatory response. After recognition of an inflammatory stimulus, these phagocytic cells become adherent, migrate in a directed manner through the blood vessel wall and/or the tissue space, ingest opsonized particulate material,
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Ca-A Cancer Journal for Clinicians, 2022
Jun J Mao,, Msce, Lorenzo Cohen, Karen M Mustian   +2 more
exaly  

Photoaffinity labelling of N-formyl peptide receptors

Pharmacology & Therapeutics, 1987
R A, Allen, A J, Jesaitis, C G, Cochrane
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Probiotic Lactobacilli activate Formyl-Peptide Receptor 2

AbstractChanges in the composition of the human microbiota can negatively impact human health. Probiotic bacteria like many lactobacilli help prevent or repair dysbiosis but it is largely unclear which molecules of these bacteria mediate the probiotic effects.
Kretschmer Dorothee, Rosenstein Ralf, Elsherbini Ahmed, Krismer Bernhard, Paul W. O’Toole, Gerlach David, Peschel Andreas   +6 more
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Formyl Peptide Receptor

2012
Erica L. Southgate, Richard D. Ye
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N-formyl peptide receptor

1997
Krishna Vaddi, Margaret Keller, Robert C. Newton   +2 more
openaire   +1 more source