Results 71 to 80 of about 18,956 (224)
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
iNew Medicine, EarlyView.ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
New formyl peptide has the stimulating properties in point of immune system cells
Annals of Mechnikov's Institute, 2019 Introduction Tuberculosis infection (TBI) is still one of the major health problems, despite of global intensive medical and pharmaceutical efforts as it is known, in the majority of immunocompetent individuals TBI is repressed by immune system, and as a
A Martynov +6 more
doaj
Retro-inverso Urokinase Receptor Antagonists for the Treatment of Metastatic Sarcomas
Scientific Reports, 2017 The development of metastases is a multistep process that requires the activation of physiological and biochemical processes that govern migration, invasion and entry of metastatic cells into blood vessels.
Maria Vincenza Carriero +13 more
doaj +1 more source
Migration of dendritic cells across blood and lymphatic endothelial barriers. [PDF]
, 2006 7openopenDel Prete A; Locati M; Otero K; Riboldi E; Mantovani A; Vecchi A; Sozzani S.DEL PRETE, Annalisa; Locati, M; Otero, K; Riboldi, E; Mantovani, A; Vecchi, A; Sozzani ...
Del Prete, Annalisa +6 more
core +1 more source
Differential Activation of Formyl Peptide Receptor-Like 1 by Peptide Ligands [PDF]
The Journal of Immunology, 2003 AbstractFormyl peptide receptor-like 1 (FPRL1) plays a key role in the regulation of immune responses. The activation of FPRL1 induces a complicated pattern of cellular signaling, which results in the regulation of several immune responses, such as chemotactic migration and the production of reactive oxygen species (ROS). Because some of these cellular
Bae, YS +8 more
openaire +3 more sources
Comparison of In‐Gel and SP3 Based Sample Preparation Protocols for LC‐MS/MS Based Proteomics
PROTEOMICS, EarlyView.ABSTRACT Sensitivity, robustness, and reproducibility of sample preparation are main determinants of data quality in bottom‐up mass spectrometry‐based proteomics. To this end, in‐gel protein clean‐up and digestion has been used for decades and is characterized by its robustness and compatibility with harsh lysis conditions.
Luisa Schwarzmüller +5 more
wiley +1 more source
Pepducin-mediated cardioprotection via β-arrestin-biased β2-adrenergic receptor-specific signaling [PDF]
, 2018 Reperfusion as a therapeutic intervention for acute myocardial infarction-induced cardiac injury itself induces further cardiomyocyte death. β-arrestin (βarr)-biased β-adrenergic receptor (βAR) activation promotes survival signaling responses in vitro ...
Benovic, Jeffrey L. +7 more
core +1 more source
Innate Immune Activity in Glomerular Podocytes [PDF]
, 2017 Glomerular podocytes are specialized in structure and play an essential role in glomerular filtration. In addition, podocyte stress can initiate glomerular damage by inducing the injury of other glomerular cell types.
Hong Xia, Shaolin Shi, Wenduona Bao
core +1 more source
Small, EarlyView.Self‐assembling amphiphilic peptide L15K6 is used as a novel immunoadjuvant for the development of a Group A Streptococcus vaccine. Robust antigen‐specific IgG responses are generated and manage to kill isolated strains of Group A Streptococcus. Cellular and bulk RNA sequencing data reveals that L15K6 regulates immune responses potentially through TLR ...
Lantian Lu +25 more
wiley +1 more source
Case Reports in Medicine, 2017 The epoxy fatty acid cis-12,13-epoxy-oleic acid, which acts as a DNA adduct, may be generated during long-term storage of many seed oils, including those used in cooking, with frying oils and fried foods being a major source in the modern human diet ...
Jean A. Monro +4 more
doaj +1 more source