Results 101 to 110 of about 43,204 (252)

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

Andrology, EarlyView.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret, Aaran H. Patel, Elisabeth Daniels, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Role of steroid hormones, estrogen receptors and metabolites in the development of endometrial hyperplasia and carcinoma

Бюллетень сибирской медицины, 2012
The integrated study of the level of hormones in systemic circulation, estrogen reception and metabolism in patients with endometrial hyperplasia and endometrial cancer has shown that the urinary level of estrogen metabolites in patients with ...
A. L. Chernyshova, L. A. Kolomiets, S. L. Stucanov   +2 more
doaj   +1 more source

Luteinizing hormone receptor knockout mouse: What has it taught us?

Andrology, EarlyView.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

FSHR Trans-Activation and Oligomerization

Frontiers in Endocrinology, 2018
Follicle stimulating hormone (FSH) plays a key role in human reproduction through, among others, induction of spermatogenesis in men and production of estrogen in women.
Kamila Szymańska, Joanna Kałafut, Alicja Przybyszewska, Beata Paziewska, Grzegorz Adamczuk, Michał Kiełbus, Adolfo Rivero-Müller, Adolfo Rivero-Müller   +7 more
doaj   +1 more source

Pesticide Exposure Alters Follicle-Stimulating Hormone Levels in Mexican Agricultural Workers [PDF]

, 2005
Organophosphorous pesticides (OPs) are suspected of altering reproductive function by reducing brain acetylcholinesterase activity and monoamine levels, thus impairing hypothalamic and/or pituitary endocrine functions and gonadal processes. Our objective
Baldi I, Butler AM, Guadalupe Ocampo-Gómez, Javier Morán-Martínez, Luisa Torres-Sánchez, Malaquías López-Cervantes, Mariano E. Cebrián, Marisela Uribe, Murray M, Nag M, Rogelio Recio, Spassova D, Victor Borja-Aburto   +12 more
core   +2 more sources

Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin

Andrology, EarlyView.
Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann, Johanna Hochmuth‐Tisch, Andrea Salzbrunn, Cord Matthies, Kathrein von Kopylow, Marta Godlewska, Christian Wülfing, Uwe Pichlmeier, Armin Soave, Christian Guido Ruf   +9 more
wiley   +1 more source

Pharmacogenetics of follicle‐stimulating hormone action in the male

Andrology, EarlyView.
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani, Giuseppe Grande, Raffele Scafa, Riccardo Selice, Andrea Garolla, Maria Santa Rocca, Cinzia Vinanzi, Alberto Ferlin   +7 more
wiley   +1 more source

Peripheral and central mechanisms involved in hormonal control of male and female reproduction [PDF]

, 2016
Reproduction involves the integration of hormonal signals acting across multiple systems togenerate a synchronized physiological output. A critical component of reproduction is the luteinizinghormone (LH) surge, which is mediated by estradiol (E2) and ...
Bentley, G. E., Calandra, Ricardo Saul, Micevych, P. E., Paredes, A. H., Rudolph, L. M., Tesone, Marta, Wu, T. J.   +6 more
core   +1 more source

Vitamin D levels and biomarkers of male fecundity: A study from the Danish National Birth Cohort

Andrology, EarlyView.
Abstract Background Vitamin D is metabolised throughout the male reproductive system, suggesting a direct regulatory role of vitamin D in male reproduction. Objectives To investigate the association between plasma vitamin D levels at sperm ejaculation and during spermatogenesis and biomarkers of male fecundity in young men.
Anne Gaml‐Sørensen, Nis Brix, Sandra Søgaard Tøttenborg, Christian Lindh, Karin Sørig Hougaard, Siri Eldevik Håberg, Gunnar Toft, Jens Peter Ellekilde Bonde, Cecilia Høst Ramlau‐Hansen   +8 more
wiley   +1 more source