Results 91 to 100 of about 15,824,548 (164)

Expression of Tas1 taste receptors in mammalian spermatozoa [PDF]

open access: yes, 2012
Background: During their transit through the female genital tract, sperm have to recognize and discriminate numerous chemical compounds. However, our current knowledge of the molecular identity of appropriate chemosensory receptor proteins in sperm is ...
Ulrich Boehm (180339)   +60 more
core   +1 more source

Regulation of G protein-coupled receptors by palmitoylation and cholesterol

open access: yesBMC Biology, 2012
Due to their membrane location, G protein-coupled receptors (GPCRs) are subject to regulation by soluble and integral membrane proteins as well as membrane components, including lipids and sterols.
Goddard Alan D, Watts Anthony
doaj   +1 more source

Acidic Tumor Microenvironment and pH-Sensing G protein-Coupled Receptors

open access: yesFrontiers in Physiology, 2013
The tumor microenvironment is acidic due to glycolytic cancer cell metabolism, hypoxia, and deficient blood perfusion. It is proposed that acidosis in the tumor microenvironment is an important stress factor and selection force for cancer cell somatic ...
Calvin R. Justus   +2 more
doaj   +1 more source

Role of G protein coupled receptors in acute kidney injury

open access: yesCell Communication and Signaling
Acute kidney injury (AKI) is a clinical condition characterized by a rapid decline in kidney function, which is associated with local inflammation and programmed cell death in the kidney.
Liangjing Lv   +7 more
doaj   +1 more source

G protein coupled receptors.

open access: yes
This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers G protein coupled receptors and includes chapters on such topics as post-translation ...
Conn, P. Michael.
core  

G protein-coupled receptors in cardiac biology: old and new receptors

open access: yes, 2015
G protein-coupled receptors (GPCRs) are seven-transmembrane-spanning proteins that mediate cellular and physiological responses. They are critical for cardiovascular function and are targeted for the treatment of hypertension and heart failure ...
Thomas, Walter   +5 more
core   +1 more source

Functionalized ligands targeting G protein-coupled adenosine receptors

open access: yes, 2019
Adenosine receptors are G protein-coupled receptors involved in important physio-pathological conditions. For this reason, from their discovery, the research of potent and selective ligands attracted the interest of researchers working in the field ...
Federico S., Spalluto G.
core   +1 more source

A systems and molecular analysis of G protein-mediated signalling [PDF]

open access: yes
The ability of cells to respond correctly to signals from their microenvironment is an essential prerequisite of life. Many external signals are detected through G protein-coupled receptor (GPCR) signalling pathways, which control all aspects of ...
Croft, Wayne D.
core  

Receptors of peptide hormones in the gut of rice brown planthopper (Nilaparvata lugens) as targets for novel insecticides [PDF]

open access: yes, 2004
The rice brown planthopper, Nilaparvata lugens, is a pest of rice where it can be responsible for single season crop losses of up to 38% (IRRI statistic).
Price, Daniel Richard Glenfield
core  

Latest surface plasmon resonance advances for G protein-coupled receptors

open access: yesJournal of Pharmaceutical Analysis
G protein-coupled receptors (GPCRs) are a big family of membrane proteins which represent one of the main classes of drug targets. However, their investigation presents several challenges, among which their instability outside the membrane environment ...
Giulia De Soricellis   +7 more
doaj   +1 more source

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