Results 201 to 210 of about 793,543 (339)

Decoding missense variants pleiotropy in the immune GPCR P2RY8. [PDF]

Cell Genom
Shen S, Luo R, Shao Z.
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Evolutionary conservation of dopamine-mediated cellular plasticity in Arctic sponges (Porifera). [PDF]

Front Mol Biosci
Kravchuk OI, Finoshin AD, Nikishina YO, Melnikova VI, Kublanov IV, Sutormin DA, Rusanova AN, Ri MT, Isaev AB, Mikhailov KV, Ziganshin RH, Adameyko KI, Anashkina AA, Ignatyuk VM, Gornostaev NG, Voronezhskaya EE, Sokolova AM, Mikhailov VS, Lyupina YV.   +18 more
europepmc   +1 more source

Targeting G protein–coupled receptor kinases to G protein–coupled receptors

Current Opinion in Endocrine and Metabolic Research, 2021
Sarah M. Sulon, Jeffrey L. Benovic
openaire   +2 more sources

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

G protein-coupled receptors in prostate cancer: research progress and therapeutic targets. [PDF]

Front Cell Dev Biol
Xiong W, Zhou B, Shi J, Ni D, Xiong Z.
europepmc   +1 more source

Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors

Cell, 2017
X. E. Zhou, Yuanzheng He, Parker W. de Waal, Xiang Gao, Yanyong Kang, N. Van Eps, Yanting Yin, K. Pal, Devrishi Goswami, Thomas A. White, A. Barty, Naomi R. Latorraca, H. Chapman, Wayne L Hubbell, R. Dror, Raymond C. Stevens, V. Cherezov, V. Gurevich, Patrick R. Griffin, Oliver P. Ernst, K. Melcher, H. E. Xu   +21 more
semanticscholar   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Dissociation kinetics of G proteins from G protein-coupled receptors and effects of allosteric modulation. [PDF]

Proc Natl Acad Sci U S A
Wang J, Nguyen ATN, Adediwura VA, Lu CS, McNeill SM, Jörg M, Scammells PJ, Christopoulos A, May LT, Miao Y.   +9 more
europepmc   +1 more source

International Union of Basic and Clinical Pharmacology. XCIII. The Parathyroid Hormone Receptors—Family B G Protein–Coupled Receptors

Pharmacological Reviews, 2015
T. Gardella, J. Vilardaga
semanticscholar   +1 more source