Results 181 to 190 of about 527,566 (280)

From bugs to brain: unravelling the GABA signalling networks in the brain-gut-microbiome axis. [PDF]

Brain
Belelli D, Lambert JJ, Wan MLY, Monteiro AR, Nutt DJ, Swinny JD.   +5 more
europepmc   +1 more source

Role of astrocyte in neuroinflammation‐induced loss in neuroplasticity and subsequent onset of depression: A systematic review

Neuroprotection, EarlyView.
Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal, Saurabh Singhal, Bernhard T. Baune   +2 more
wiley   +1 more source

Dexmedetomidine promotes colorectal cancer progression mediated by gamma-aminobutyric acid signaling. [PDF]

Cancer Metab
Dong J, Wu Y, Che J, He Z, Zhang J.
europepmc   +1 more source

Elucidating the Three‐Dimensional Structure of Piracetam through Rotational Spectroscopy

ChemistryOpen, EarlyView.
Neutral molecules of the nootropic drug piracetam are generated by laser ablation and structurally characterized by microwave spectroscopy. Two conformers differing in the exo/endo configuration of the pyrrolidine ring are detected, with exo being the predominant form.
S. Mato, S. Municio, J. L. Alonso, E. R. Alonso, I. León   +4 more
wiley   +1 more source

GABA_B receptor activation contributes to post-surgery cognitive impairments in mice by inducing hippocampal BDNF hypermethylation. [PDF]

Ann Med
Wu T, Sun XY, Cao J, Tong K, Hao JR, Sun N, Gao C.   +6 more
europepmc   +1 more source

Unveiling the Therapeutic Potential of Atractylis aristata Batt. Aqueous Extract: Anti‐inflammatory, Antioxidant, Antibacterial, Sedative Activities & Phytochemical Profiling

ChemistryOpen, EarlyView.
This study evaluates the pharmacological properties of the aqueous extract of Atractylis aristata, focusing on its antioxidant, anti‐inflammatory, antibacterial, and sedative activities. Phytochemical analysis identifies bioactive compounds, while in vitro and in vivo tests demonstrate its therapeutic potential in addressing oxidative stress ...
Asma Abid, Nourelhouda Mekhadmi, Randa Mlik, Assia Bentahar, Kamilia Bireche, Bariza Frih, Walid Boussebaa, Aicha Mouane, Nezar Cherrada, Ana Sanches Silva, Messaouda Dekmouche, Lazhar Bechki, Khalid Mashay Al‐Anazi, Mohammad Abul Farah, Ahmad Ali   +14 more
wiley   +1 more source

Tea and Its Active Ingredients in Preventing and Alleviating Depression: A Comprehensive Review. [PDF]

Foods
Xiao S, Li Y, Jiang H, Hou S, Wang Y, Wang D, Teng J.   +6 more
europepmc   +1 more source

Abrupt and Severe Onset of Dystonia, Chorea and Hemiplegic Episodes in a Young Boy with a Novel Heterozygous Missense Variant in the GTPase Domain of RHOBTB2

Movement Disorders Clinical Practice, EarlyView.
Phuong T. Hoang, Ian O. Bledsoe, Marta San Luciano   +2 more
wiley   +1 more source

Neuroprotective Efficacy of Microwave‐Assisted Synthetized 2‐(5‐Cyclopropyl‐6‐Thioxo‐1,3,5‐Thiadiazinan‐3‐Yl) Acetic Acid in Mitigating Cognitive Deficits in Pentylenetetrazole‐Induced Mice Model

ChemistryOpen, EarlyView.
Microwave synthesis yielded 2‐(5‐cyclopropyl‐6‐thioxo‐1,3,5‐thiadiazinan‐3‐yl)acetic acid, confirmed by infrared, nuclear magnetic resonance, and electron ionization mass spectrometry. In a pentylenetetrazole‐induced epilepsy model, it countered oxidative stress by boosting antioxidant enzymes (catalase, peroxidase, superoxide dismutase, glutathione ...
Tahir Iqbal, Murad A. Mubaraki, Ahmad Khushal, Amena Arif, Fozia Fozia, Shahid Ali Shah, Ijaz Ahmad, Rasool Khan, Najeeb Ur Rehman, Ziaullah Ziaullah   +9 more
wiley   +1 more source

From the different pathogenesis of epileptogenesis: vitamins as an adjunctive treatment for epilepsy. [PDF]

Acta Epileptol
Sun W, Wang Y, Xiao B, Luo Z.
europepmc   +1 more source