Results 161 to 170 of about 449,457 (314)

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

GABA_A Receptor Modulators as Emerging Therapeutic Agents for Depressive Disorders. [PDF]

Drug Des Devel Ther
Guan BY, Li Y.
europepmc   +1 more source

GABA receptor [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

The endogenous cannabinoid system gates plasticity of tonic GABA inhibition. [PDF]

J Physiol
Colangeli R, Conti F.
europepmc   +1 more source

GABA RECEPTORS AND BENZODIAZEPINES

British Journal of Anaesthesia, 1993
openaire   +2 more sources

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Direct modulation of human GABA-A α₁β₂γ₂ receptors by the endocannabinoid 2-arachidonoylglycerol: implications for cannabinoid-related ligands and limitations for anxiolytic drug development. [PDF]

Front Neurosci
Mixcoha E, Flores-Zamora A, Hernández-Miramontes R, Hernández-Calderón JA, Martiñón S.   +4 more
europepmc   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Alterations in the Components of the GABA-Glutamate System During ZIKV Infection: A Neuroscience Approach. [PDF]

Int J Mol Sci
Rengifo AC, Naizaque J, Santamaría G, Alvarez-Díaz DA, Rodriguez AV, Guío-Vega G, Rivera J, Castro CE, Dueñas Z, Torres-Fernández O.   +9 more
europepmc   +1 more source