Results 111 to 120 of about 159,633 (311)

Effect of administration gamma-amino butyric acid on physiological performance of broiler chicks [PDF]

open access: yesarXiv, 2020
This experiment was conducted to study the effect of administration {\gamma}-amino butyric acid (GABA) on physiology performance of broiler chicks. The following treatments were used: T1:control treatment, T2: the birds were administration 0.2ml 0.4% GABA solution daily, T3: the birds were administration 0.2ml 0.5% GABA solution daily and T4: the birds
arxiv  

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

open access: yesBMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu   +7 more
wiley   +1 more source

Allosteric Modulation of αβδ GABAA Receptors

open access: yesPharmaceuticals, 2010
GABAA receptors mediate the majority of the fast inhibition in the mature brain and play an important role in the pathogenesis of many neurological and psychiatric disorders.
Hua-Jun Feng
doaj   +1 more source

Inhibition of activity of GABA transporter GAT1 by δ-opioid receptor [PDF]

open access: yes, 2012
Analgesia is a well-documented effect of acupuncture. A critical role in pain sensation plays the nervous system, including the GABAergic system and opioid receptor (OR) activation.
Fucke, Thomas   +7 more
core   +2 more sources

How transcranial direct current stimulation facilitates post-stroke rehabilitation [PDF]

open access: yesarXiv, 2019
Whether transcranial direct current stimulation (tDCS) benefits stroke rehabilitation remains unclear. To investigate how tDCS reorganizes brain circuitry, nineteen post-stroke patients underwent rehabilitation sessions with bi-hemispheric real vs sham tDCS intervention. Resting motor threshold measurements showed tDCS evoked higher excitability in the
arxiv  

Effects of the GABA(B) agonist baclofen on volitional swallowing in normal subjects

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 39, Issue 1, Page 80-86, January 2023., 2023
Abstract The GABA(B) receptor agonist baclofen is known to suppress the rate of spontaneous swallowing but not pharyngeal muscle contraction. The extent to which baclofen may alter volitional swallowing is not currently known. We investigated the effects of baclofen in healthy subjects, hypothesizing that baclofen exposure would alter volume‐regulation
Jui‐Sheng Hung   +8 more
wiley   +1 more source

Enhancing antitumor immunity through the combination of cholesterolized TLR7 agonist liposomes and radiotherapy: a role for IL‐1β and the inflammasome pathway

open access: yesCancer Communications, EarlyView.
Abstract Background Radiotherapy (RT) is a key treatment modality in cancer therapy, utilizing high‐energy radiation to directly kill tumor cells. Recent research has increasingly highlighted RT's potential to indirectly enhance antitumor immunity. However, this immune activation alone often fails to generate sustained systemic antitumor responses.
Xuejiao Han   +11 more
wiley   +1 more source

Co-operative Effect Between γ-Aminobutyric Acid A Receptors and Central-Type Benzodiazepine Receptors on Amylase Release in Rat Parotid Acinar Cells

open access: yesJournal of Pharmacological Sciences, 2010
We investigated the inhibitory role of γ-aminobutyric acid A (GABA A ) receptors on amylase release and the evidence for functional coupling with central-type benzodiazepine receptors in rat parotid acinar cells.
Migiwa Okubo, Mitsuru Kawaguchi
doaj  

Isovaline does not activate GABA(B) receptor-coupled potassium currents in GABA(B) expressing AtT-20 cells and cultured rat hippocampal neurons.

open access: yesPLoS ONE, 2015
Isovaline is a non-proteinogenic amino acid that has analgesic properties. R-isovaline is a proposed agonist of the γ-aminobutyric acid type B (GABA(B)) receptor in the thalamus and peripheral tissue.
Kimberley A Pitman   +3 more
doaj   +1 more source

Antagonists of Ionotropic Receptors for the Inhibitory Neurotransmitter GABA: Therapeutic Indications [PDF]

open access: yes, 2018
Agents that antagonize the action of GABA on ionotropic receptors are widely used to probe the function of this neurotransmitter. Three such agents are in common use: bicuculline, gabazine, and picrotoxinin.
Hinton, Tina, Johnston, Graham A. R.
core   +1 more source

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