Results 261 to 270 of about 2,453,144 (355)

Mechanisms of alcohol influence on fear conditioning: A computational model

Alcohol, Clinical and Experimental Research, EarlyView.
Computational models can test mechanistic relationships between fear conditioning, neuroadaptations, and alcohol. Simulated fear extinction is slower and less robust under alcohol, as greater basolateral amygdala activation is needed. Alcohol shifts the amygdala network away from robust extinction by inhibiting central amygdala activity.
Adam Lonnberg, Marian L. Logrip, Alexey Kuznetsov   +2 more
wiley   +1 more source

Possible GABAkine-Mediated Sedative-Like Antidepressant Effects of Phytol: Molecular Interventions Through In Vitro, In Vivo and In Silico Approaches. [PDF]

CNS Neurosci Ther
Islam MT, Ferdous J, Hasan MSA, Bhuia MS, Ansari IA, Ansari SA, Islam MA, Saifuzzaman M.   +7 more
europepmc   +1 more source

Altered activity within the social behavior neural network in adolescent rats following prenatal alcohol exposure and/or early‐life adversity

Alcohol, Clinical and Experimental Research, EarlyView.
Prenatal alcohol exposure (PAE) and early‐life adversity (ELA) independently and interactively disrupted neural activity within the social behavior network in adolescent rats, with age‐ and sex‐specific effects. PAE primarily dampened amygdala activity, while ELA altered medial prefrontal cortex responses. These findings reveal how different early‐life
Parker J. Holman, Linda Ellis, Amanda Chao, Cecilia Mitchell, Charlis Raineki, Joanne Weinberg   +5 more
wiley   +1 more source

Rodent islet amyloid polypeptide (IAPP) selectively enhances GABA _<i>A</i> receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells. [PDF]

Front Cell Neurosci
Netsyk O, Korol SV, Westermark GT, Birnir B, Jin Z.   +4 more
europepmc   +1 more source

Human Pulmonary Neuroendocrine Cells Respond to House Dust Mite Extract With PAR‐1 Dependent Release of CGRP

Allergy, Volume 80, Issue 4, Page 976-985, April 2025.
This study aimed to develop and characterize an in vitro human PNEC model and investigated the neuroendocrine response to HDM extract. Exposure to HDM leads to dose‐dependent induction of the CGRP encoding gene, CALCB, and corresponding release of the neuropeptide.
Ritu Mann‐Nüttel, Shivani Mandal, Marie Armbruster, Lakshmi Puttagunta, Paul Forsythe   +4 more
wiley   +1 more source

Alcohol and alcoholism associated neurological disorders: Current updates in a global perspective and recent recommendations. [PDF]

World J Exp Med
Sahu P, Verma HK, Bhaskar L.
europepmc   +1 more source

La femme fait la maison: The Accumulation of Surplus Value through Family Planning in Burkina Faso1

Antipode, EarlyView.
Abstract Since the 1960s, demographers, international donors, and governments have calculated the political, economic, and social benefits of modern contraception usage in West Africa. We evidence how family planning technologies (FPTs) that are tethered to population development extract double value (productive and reproductive labour) from Burkinabè ...
T.D. Harper‐Shipman, Katian Napon
wiley   +1 more source

Insights and progress on the biosynthesis, metabolism, and physiological functions of gamma-aminobutyric acid (GABA): a review. [PDF]

PeerJ
Zhang Q, Zhu L, Li H, Chen Q, Li N, Li J, Zhao Z, Xiao D, Tang T, Bi C, Zhang Y, Zhang H, Zhang G, Li M, Zhu Y, Zhang J, Kong J.   +16 more
europepmc   +1 more source

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

Acta Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs, Berith M. Balfoort, Marion M. Brands, Anneloor L. M. A. ten Asbroek, Camiel J. F. Boon, Roselie M. H. Diederen, Corrie Timmer, Margreet A. E. M. Wagenmakers, Hans R. Waterham, Ronald J. A. Wanders, Riekelt H. Houtkooper, Clara D. van Karnebeek, Arthur A. Bergen   +12 more
wiley   +1 more source

Early Polytherapy for Probably Benzodiazepine Refractory Naïve Status Epilepticus (Stage 1 Plus). [PDF]

Neurol Int
Magro G.
europepmc   +1 more source