Results 71 to 80 of about 29,825 (276)

Relationship of Ghrelin and Ghrelin Receptor Polymorphisms with Type 2 Diabetes

, 2022
There is compelling evidence that the gastric peptide ghrelin and its growth hormone secretagogue G protein-coupled receptor play an important role in glucose metabolism and energy homeostasis. Therefore, these genes carrying susceptibility alleles for Type 2 diabetes are considered as potential candidates.A case-control cross-sectional association ...
Özkahraman, Didem, Selçuk, Esma, Şahin Calapoğlu, Nilüfer, Calapoğlu, Mustafa, Şahin, Uğur   +4 more
openaire   +3 more sources

Ghrelin receptor in GtoPdb v.2023.1

IUPHAR/BPS Guide to Pharmacology CITE, 2023
The ghrelin receptor (nomenclature as agreed by the NC-IUPHAR Subcommittee for the Ghrelin receptor [19]) is activated by a 28 amino-acid peptide originally isolated from rat stomach, where it is cleaved from a 117 amino-acid precursor (GHRL, Q9UBU3).
Bjørn B. Sivertsen, Janet J. Maguire, Matthias Kleinz, Birgitte Holst, Anthony P. Davenport   +4 more
openaire   +1 more source

PERCC1‐associated enteropathy: Diagnostic challenges and enteral autonomy achieved with teduglutide

JPGN Reports, EarlyView.
Abstract Congenital diarrheas and enteropathies (CODE) are rare inherited disorders characterized by early‐onset intractable diarrhea. Though progress has been made in elucidating the genetic basis of CODE, much remains to be discovered. Another challenge is the lack of curative therapies—treatment is primarily supportive including enteral and ...
Angela Tran, Vivien Nguyen, Phuong Huynh
wiley   +1 more source

Mouse circadian plasma leptin and active ghrelin rhythms under ad libitum and scheduled feeding [PDF]

, 2007
Thesis (M.S.) University of Alaska Fairbanks, 2007Light is the strongest timing cue for the circadian system, but non-photic cues can also entrain the master circadian clock, i.e., suprachiasmatic nuclei (SCN).
Wan, Haiting
core  

Intragastric infusion of the bitter tastant quinine suppresses hormone release and antral motility during the fasting state in health female volunteers [PDF]

, 2017
Intragastric administration of the bitter tastant denatonium benzoate inhibits the increase of motilin plasma levels and antral contractility. While these findings suggest that gastrointestinal bitter taste receptors could be new targets to modulate ...
Andreozzi, Avau, Avesaat, Carlson, Chen, Chen, Code, Date, Deloose, Deloose, Dooley, Gutierrez, Hellstrom, Hofer, Janssen, Kaji, Kim, Kuroda, Miyano, Schier, Straub, Tack, Wang, Wicks, Wiener   +24 more
core   +2 more sources

Physiological barriers to oral intake in survivors of critical illness: A scoping review

Nutrition in Clinical Practice, EarlyView.
Abstract Oral nutrition is the predominant mode of nutrition delivery on the post–Intensive Care Unit (ICU) ward; yet, it is associated with lower intake than via enteral or parenteral nutrition. There are limited data on barriers that influence oral intake in ICU survivors.
Breanna J. Teleki, Elizabeth Viner Smith, Amy Freeman‐Sanderson, Rosalie Yandell, Lee‐anne S. Chapple   +4 more
wiley   +1 more source

Novel regulator of acylated ghrelin, CF801, reduces weight gain, rebound feeding after a fast, and adiposity in mice

Frontiers in Endocrinology, 2015
Ghrelin is a 28 amino-acid hormonal peptide that is intimately related to the regulation of food intake and body weight. Once secreted, ghrelin binds to the growth hormone secretagogue receptor-1a (GHSR-1a), the only known receptor for ghrelin and is ...
Martin K Wellman, Zachary Robert Patterson, Harry eMackay, Joseph E Darling, Bharath K Mani, Jeffrey eZigman, James L Hougland, Alfonso eAbizaid   +7 more
doaj   +1 more source

Significant role of the truncated Ghrelin Receptor GHS-1Rb in Ghrelin-induced signaling in neurons [PDF]

, 2016
The truncated non-signaling ghrelin receptor GHS-R1b has been suggested to simply exert a dominant negative role in the trafficking and signaling of the full and functional ghrelin receptor GHS-R1a.
Andrews, Antonio Cortés, Bennett, Bonaventura, Carme Lluís, Carriba, Chen, Chow, Ciruela, Cuellar, Damian, David Aguinaga, Della Rocca, Dezaki, Dezaki, Dorn, Edgar Angelats, Enric I. Canela, Estefanía Moreno, Ferré, Gemma Navarro, Guitart, Holst, Hradsky, Jang, Jiang, Josefa Mallol, Kern, Kovacs, Leung, Malagón, Mary, Mason, Mireia Medrano, Peter J. McCormick, Schröder, Sergi Ferré, Silver, Sun, Vicent Casadó, Zimmermann   +40 more
core   +1 more source

Anorexia nervosa and reproduction: connecting brain to gonads [PDF]

, 2020
Anorexia nervosa (AN) is a psychiatric disorder that predominantly affects young women and is characterized by low caloric intake and a major dissatisfaction with one’s body image.
Ciobanu, Corina, Fica, Simona, Poterasu, Mihaela, Rowland, David L.   +3 more
core   +2 more sources

Exploring Sleep, Energy Balance, and Weight Loss Maintenance After Bariatric Surgery in Adult Females: A Cross‐Sectional Study

Obesity, EarlyView.
ABSTRACT Objective This cross‐sectional study examined associations between sleep, body weight, body composition, appetite, and food reward after bariatric surgery. Methods A single 7‐day study period in 22 female adults (age, 53.5 ± 9.3 years; BMI, 35.5 ± 8.5 kg/m2; body fat: 44.9% ± 8.6%) who underwent bariatric surgery ≥ 1 year prior to enrollment ...
Hannah R. Koch, Derek C. Monroe, Steve Fordahl, Graham Finlayson, Laurie Wideman, Jessica McNeil   +5 more
wiley   +1 more source