Results 231 to 240 of about 175,721 (299)

S100A8/A9‐High Macrophages Activate Intestinal Fibroblasts via mCCL6/hCCL15‐CCR1 Axis to Drive Intestinal Fibrosis in Crohn's Disease

open access: yesAdvanced Science, EarlyView.
S100A8/A9‐high macrophages are markedly enriched in the stenotic intestinal tissue of patients with Crohn's disease. These profibrotic macrophages secrete mCCL6 in a STAT3‐dependent manner. mCCL6 and its human ortholog hCCL15 activate fibroblasts via the CCR1 receptor, thereby driving excessive collagen deposition.
Shu Wang   +12 more
wiley   +1 more source

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

open access: yesAdvanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou   +11 more
wiley   +1 more source

Dry‑Contact Trimming for All‑Perovskite Tandem Solar Cells via Solid‑Solution Homogenization

open access: yesAdvanced Energy Materials, EarlyView.
Narrow‐bandgap Sn–Pb perovskites are promising bottom absorbers for all‐perovskite tandems but suffer from Sn‐rich surfaces and depth‐dependent lattice/compositional inhomogeneity. Layered‐perovskite‐assisted dry‐contact trimming removes Sn‐rich surface species and reconfigures the Sn–Pb absorber, enabling efficient charge collection, reduced voltage ...
Woocheol Han   +10 more
wiley   +1 more source

Glycine receptors in circulating white blood cells regulated by neuroinflammation. [PDF]

open access: yesFront Immunol
Thakur V   +11 more
europepmc   +1 more source

Effects of Outsourced Agricultural Extension Services on the Technical Efficiency and Financial Returns of Soybean Farms in Northern Cameroon

open access: yesAgribusiness, EarlyView.
ABSTRACT In the agricultural landscape of most developing countries, the last decade has witnessed the expansion of outsourced agricultural extension services. Private firms and nongovernmental organizations focused on delivering agricultural extension and advisory services to farmers have emerged.
Boris D. Soh Wenda   +3 more
wiley   +1 more source

Crosstalk Between Glycinergic and N-Methyl-D-Aspartate Receptor-Mediated Glutamatergic Transmission in Behaviours Associated with Opioid Use Disorder. [PDF]

open access: yesInt J Mol Sci
Essmat N   +13 more
europepmc   +1 more source

Therapeutic inhibition of HBsAg and HBV cccDNA through a novel phased combination treatment: glycine and interferon-α. [PDF]

open access: yesGut
Lin C   +13 more
europepmc   +1 more source

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