Results 101 to 110 of about 2,977,129 (352)

Immunohistochemical evaluation of human epidermal growth factor receptor 2 and estrogen and progesterone receptors in breast carcinoma in Jordan [PDF]

, 2005
INTRODUCTION: Although breast carcinoma (BC) is the most common malignancy affecting Jordanian females and the affected population in Jordan is younger than that in the West, no information is available on its biological characteristics. Our aims in this
AA Abalkhail, AM Ruder, B Zafrani, CR De Potter, CW Elston, D Varshney, DC Allred, DH Choi, DJ Slamon, DJ Slamon, DJ Slamon, E May, Early Breast Cancer Trialists' Collaborative Group, ER Hoff, F Revillion, G Abadjian, G Arpino, G Pauletti, G Pauletti, GN Hortobagyi, HB Muss, J Ashba, J Yang, JA Ligibel, JM Esteban, Jordan Cancer Registry, Ministry of Health, JS Huston, JS Ross, K McKeage, LC Hartmann, LJ Layfield, LK Shawver, M Ferno, M Stierer, MF Kamal, Mohammad Al Hamad, Nidal M Almasri, O Stal, PL Porter, RH Mohammed, S Chariyalertsak, S Eppenberger-Castori, S Paik, S Taucher, SI Rosenthal, SS Amr, T el-A Helal, T Rajkumar, U Berger, W Hanna, WF Anderson, YF Dajani   +51 more
core   +2 more sources

Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors.

Science, 1990
Phospholipase C gamma 1 (PLC gamma 1) and p21ras guanosine triphosphatase (GTPase) activating protein (GAP) bind to and are phosphorylated by activated growth factor receptors.
D. Anderson, C. Koch, L. Grey, C. Ellis, M. Moran, T. Pawson   +5 more
semanticscholar   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

GROWTH FACTOR AND ADIPOKINE RECEPTORS IN PATHOGENESIS AND PROGNOSIS OF ENDOMETRIAL CANCER IN PATIENTS WITH METABOLIC SYNDROME

Сибирский онкологический журнал, 2016
The role of growth factor receptors (insulin-like growth factor and transforming growth factor-beta) and adipokine receptors (leptin and adiponectin) in pathogenesis of endometrial cancer under conditions of metabolic syndrome is discussed ...
N. V. Yunusova, I. V. Kondakova, L. А. Kolomiets, А. L. Chernyshova, Е. V. Shanshashvili   +4 more
doaj  

Developmental process and expression patterns of fibroblast growth factor receptors in murine meniscus after birth

Di-san junyi daxue xuebao, 2019
Objective To observe the developmental process of murine meniscus after birth and investigate the expression patterns of 3 types of fibroblast growth factor receptors (FGFRs) during this process. Methods Mice at different ages (1 d old and 1, 2, 4, 6 and
LI Fangfang, XIE Yangl, HUANG Junlan, ZHANG Ruobin, JIANG Wanling   +4 more
doaj   +1 more source

Positive autoregulation of GDNF levels in the ventral tegmental area mediates long-lasting inhibition of excessive alcohol consumption. [PDF]

, 2011
Glial cell line-derived neurotrophic factor (GDNF) is an essential growth factor for the survival and maintenance of the midbrain dopaminergic (DA-ergic) neurons.
Ahmadiantehrani, S, Barak, S, Kharazia, V, Ron, D   +3 more
core   +3 more sources

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

An autocrine role for pituitary GABA: Activation of GABA-B receptors and regulation of growth hormone levels [PDF]

, 2002
There is increasing evidence suggesting that the neurotransmitter gamma-aminobutyric acid (GABA) is a local factor involved in the regulation of endocrine organs.
Corsi, C., Gamel-Didelon, Katia, Gratzl, M., Jung, H., Mayerhofer, Artur, Pepeu, G.   +5 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source