Growth Factor Receptors and Apoptosis Regulators: Signaling Pathways, Prognosis, Chemosensitivity and Treatment Outcomes of Breast Cancer [PDF]
Breast Cancer: Basic and Clinical Research, 2009 Biomarkers of breast cancer are necessary for prognosis and prediction to chemotherapy. Prognostic biomarkers provide information regarding outcome irrespective of therapy, while predictive biomarkers provide information regarding response to therapy ...
Siddik Sarkar, Mahitosh Mandal
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The insulin-like growth factor system and its receptors: A potential novel anticancer target
Biologics: Targets & Therapy, 2008 Colin R. Lindsay1, T R Jeffry Evans1,21Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom; 2University of Glasgow, CR-UK Beatson Laboratories, Garscube Estate, Glasgow, United KingdomAbstract: The current generation of novel anticancer ...
Colin R. Lindsay, T R Jeffry Evans
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The complete family of epidermal growth factor receptors and their ligands are co-ordinately expressed in breast cancer [PDF]
, 2009 The levels of expression of the four receptors and eleven ligands composing the Epidermal Growth Factor family were measured using immunohistochemical staining in one hundred cases of breast cancer. All of the family were expressed to some degree in some
McIntyre, Emmet +4 more
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Update on HER-2 as a target for cancer therapy: alternative strategies for targeting the epidermal growth factor system in cancer [PDF]
, 2001 The epidermal growth factor (EGF) family of ligands and receptors interact to influence cell division, differentiation and motility. Much evidence supports their importance in causing and sustaining cell transformation in model systems and in human ...
Gullick, William J.
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An autocrine role for pituitary GABA: Activation of GABA-B receptors and regulation of growth hormone levels [PDF]
, 2002 There is increasing evidence suggesting that the neurotransmitter gamma-aminobutyric acid (GABA) is a local factor involved in the regulation of endocrine organs.
Corsi, C. +5 more
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The mitogenic potential of heparin-binding epidermal growth factor in the human endometrium is mediated by the epidermal growth factor receptor and is modulated by tumor necrosis factor-alpha [PDF]
, 2002 Heparin-binding epidermal growth factor (HB-EGF), a member of the epidermal growth factor (EGF) family, is implicated in a variety of biological processes, including reproduction.
Mardon, Helen J. +23 more
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Role of Glycans on Key Cell Surface Receptors That Regulate Cell Proliferation and Cell Death
Cells, 2021 Cells undergo proliferation and apoptosis, migration and differentiation via a number of cell surface receptors, most of which are heavily glycosylated.
Yin Gao +3 more
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Cytokine & growth factor reviews, 2015 The four receptor tyrosine kinases (RTKs) within the family of Fibroblast Growth Factor Receptors (FGFRs) are critical for normal development but also play an enormous role in oncogenesis.
Leandro H. Gallo +3 more
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Cancer Cell International, 2006 Background Somatostatin receptor (SSTR) expression is positively correlated with tumor size and inversely correlated with epidermal growth factor receptor (ErbB) levels and tumor differentiation. In the present study, we compared SSTR1-5 and ErbB1-4 mRNA
Kumar Ujendra, Watt Heather L
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Frontiers in Oncology, 2023 Nintedanib is a tyrosine kinase inhibitor of fibroblast growth factor-, vascular endothelial growth factor-, and platelet-derived growth factor receptors.
Shu Yan +6 more
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