Adjuvant Metronomic Chemotherapy After Surgery in pT1-T2 N0 M0 HER2-Positive and ER/PR-Positive Breast Cancer Plus Targeted Therapy, Anti-Hormonal Therapy, and Radiotherapy, with or Without Immunotherapy: A New Operational Proposal. [PDF]
Cancers (Basel)Roncati L.
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Research progress on estrogen receptor-positive/progesterone receptor-negative breast cancer. [PDF]
Transl OncolLu Z, Wang T, Wang L, Ming J.
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Wnt signaling pathways in biology and disease: mechanisms and therapeutic advances. [PDF]
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Lipid rafts: novel therapeutic targets for metabolic, neurodegenerative, oncological, and cardiovascular diseases. [PDF]
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Proinflammatory Cytokines in Chronic Respiratory Diseases and Their Management. [PDF]
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Growth factors and their receptors
Current Opinion in Cell Biology, 1989The growth of cells in culture is controlled by polypeptide hormones that stimulate or inhibit proliferation. More than 20 different growth factors have been extensively characterised, and the corresponding cDNAs have been cloned (Table 1). Several additional growth factors are known from their biological activities but have not yet been structurally ...
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Growth Factors and Their Receptors
Hematology/Oncology Clinics of North America, 1994Breast cancer represents a type of malignancy that is amenable to therapy targeting growth factors and receptors. There is considerable evidence that signaling mechanisms involving growth factors and their receptors are important in the normal development of breast epithelium.
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Growth Factor Receptors: The Epidermal Growth Factor Receptor as a Model [PDF]
, 1990 Secreted polypeptide growth factors such as insulin, insulinlike growth factor I (IGF-I), epidermal growth factor (EGF), platelet-derived growth factor (PDGF), and colony-stimulating factor (CSF-1) initiate complex cytoplasmic and nuclear events. These distinct cellular responses can be attributed to the interaction of hormones with their respective ...
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Keratinocyte Growth Factor Receptors
Dermatologic Clinics, 2007Modulation of the number of functional growth factor receptors on the epithelial cell surface that is exposed to the action of cognate ligands represents a key strategy in cellular physiology to regulate the proliferation rate and the differentiation process. The keratinocyte growth factor receptor (KGFR) and the epidermal growth factor receptor (EGFR),
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