Results 231 to 240 of about 89,612 (317)

Clinical Characteristics and Outcomes of Patients With Rome IV Functional Dyspepsia Who Consume Opioids: A Real‐World Study

open access: yesNeurogastroenterology &Motility, EarlyView.
Approximately one in three patients with Rome IV functional dyspepsia (FD) consume opioids and this is associated with older age, depression/anxiety, and chronic pain. Opioid cessation alongside a neuromodulator improved symptoms in 29% of cases, with a number needed to treat of 5.7, suggesting that this treatment strategy may be beneficial in FD ...
Mohsin F. Butt   +9 more
wiley   +1 more source

Use of Human In Vitro Gut Specimens for Translational Neurogastroenterology and Motility in the 21st Century

open access: yesNeurogastroenterology &Motility, EarlyView.
In vitro studies with GI surgical specimens or biopsy are a critical step in translating preclinical studies in animals to humans before testing potential therapeutic interventions in expensive clinical trials. Routine availability of human gut specimens, in combination with technological advances and powerful new in vitro models of the human ENS from ...
Dmitrii Pavlov, Fievos L. Christofi
wiley   +1 more source

Impact of Opioid and Cannabis Use on Low‐Dose Amitriptyline Efficacy in Cyclical Vomiting Syndrome: A Real‐World Study in the United Kingdom

open access: yesNeurogastroenterology &Motility, Volume 37, Issue 6, June 2025.
This article presents the outcomes of a three‐tiered outpatient treatment algorithm for the prophylactic management of cyclical vomiting syndrome (CVS). Three key messages: (1) 61% of patients responded to the treatment algorithm, (2) opioid cessation was associated with clinical response to the treatment algorithm (p = 0.03), and (3) a low‐dose ...
Mohsin F. Butt   +4 more
wiley   +1 more source

Screening of neurotransmitter receptor modulators reveals novel inhibitors of influenza virus replication. [PDF]

open access: yesFront Cell Infect Microbiol
Gao Y   +12 more
europepmc   +1 more source

Defective lymphatic vasculature in obesity

open access: yesObesity Reviews, EarlyView.
Summary Lymphedema is an important, and often underdiagnosed complication of obesity and is likely due to acquired defects in the lymphatic vasculature. Study of diet‐induced obesity animal models have indicated defective lymphatic vasculatures might extend to other anatomical sites, especially visceral depots.
Jingjing Zhu, John P. H. Wilding, Ji Hu
wiley   +1 more source

Deciphering Histamine Pathway Networks in the Human Brain: A Multimodal Approach to Cognition and Psychiatric Disorders

open access: yes
Martins D   +7 more
europepmc   +1 more source

Ovarian Cancer G protein-coupled receptor-1 signaling bias dictates anti-contractile effect of benzodiazepines on airway smooth muscle. [PDF]

open access: yesRespir Res
Villalba DR   +10 more
europepmc   +1 more source

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