Results 71 to 80 of about 53,739 (211)
Early life adversity has been established as a major risk factor for the development of inflammatory disease as well as increased mortality in humans. In swine production, weaning is a necessary practice, but is also the most stressful life event that a ...
Thelen, Kyan
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Molecular Pharmacology of the Four Histamine Receptors
Histamine and its receptors have been (and are still today) very fruitful topics for pharmacological and medicinal chemistry studies. In this chapter we review the various selective ligands that are available for the four different histamine receptors ...
Bongers, G +3 more
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The role of the histamine H3 receptor (H3R) in anxiety is controversial, due to limitations in drug selectivity and limited validity of behavioral tests used in previous studies. In the present report, we describe two experiments.
Paul L. Chazot +9 more
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Targeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal [PDF]
Irritable bowel syndrome is a group of functional gastrointestinal disorders with not yet fully clarified etiology. Recent evidence suggesting that mast cells may play a central role in the pathogenesis of irritable bowel syndrome paves the way for ...
Martin Storr +9 more
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Histamine receptors and cancer pharmacology : an update
: In the present review, we will discuss the recent advances in the understanding of the role of histamine and histamine receptors in cancer biology. The controversial role of the histaminergic system in different neoplasias including gastric, colorectal,
Massari, Noelia A. +2 more
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Histamine receptors mediating vascular responses in brain [PDF]
Several facts suggest that histamine may influence the function of cerebral blood vessels. 1) Histamine has important vascular effects in non-neural organs; 2) Cerebral microvessels and arteries contain receptors for histamine; 3) Enzyme systems in brain
Gross, Paul Munn
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O neuropeptídio Y (NPY) na medula espinhal medeia o efeito hiponociceptivo da ativação de receptores H1 histaminérgicos na articulação do joelho de ratos [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2013.A histamina é encontrada no líquido sinovial de indivíduos saudáveis e pacientes com diversos tipos ...
Silva, Eduardo Souza
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Activation of Microglia by Histamine and Substance P
Background: Activated microglia perform many of the immune effector functions typically associated with macrophages. However, the regulators involved in microglial activation are not well defined.
Jin Zhu, Chen Qu, Xiang Lu, Shu Zhang
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Network perspective of histamine related diseases. [PDF]
Histamine is the most pleiotropic biogenic amine. Produced and stored by a limited set of cells—histaminergic neurons, enterochromaffin-like cells, and mast cells—it broadcasts intercellular communication signals to a wide variety of cell types through ...
Medina-Torres, Miguel Ángel +6 more
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The consumption of food containing high amounts of histamine and other biogenic amines can cause food poisoning with different symptoms linked to the individual sensitivity and the detoxification activity.
Rosanna Tofalo +7 more
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