Results 81 to 90 of about 53,739 (211)

Histamine H1‐receptor‐mediated modulation of NMDA receptors signaling responses

open access: yesPharmacology Research & Perspectives
This study attempted to clarify the role of histamine H1 receptors in epilepsy by exploring the effects of agonists and inverse agonists on the rundown of the current induced by iterative applications of NMDA or GABA in primary neuronal culture ...
J.‐M. Arrang, V. Armand
doaj   +1 more source

Immune regulation by histamine H4 receptors in skin

open access: yes, 2008
The diverse effects of histamine on immune regulation appear to be due to differential expression and regulation of four types of histamine receptors and their distinct intracellular signals. The differences in cellular expression and affinities of these
Akdis, C A, Akdis, Cezmi A.
core   +1 more source

Development of novel ligands influencing neurotransmission in the central nervous system

open access: yes, 2007
The development of novel drugs targeting GPCRs is of particular interest since modulation of subfamilies of this receptor class highly influences neurotransmission in the central nervous system.
Sasse, Britta Caroline
core  

Heterómeros de receptores de dopamina. Nuevos mecanismos para la regulación de la transmisión dopaminérgica [PDF]

open access: yes, 2012
[spa] El Objetivo General de esta Tesis ha sido investigar la formación y función de heterómeros entre receptores de dopamina y otros receptores que puedan estar implicados en la regulación de la transmisión dopaminérgica, como receptores de galanina ...
Moreno Guillén, Estefanía
core  

Role of Histamine in Modulating the Immune Response and Inflammation

open access: yesMediators of Inflammation, 2018
Inflammatory mediators, including cytokines, histamine, bradykinin, prostaglandins, and leukotrienes, impact the immune system, usually as proinflammatory factors.
Anna Cláudia Calvielli Castelo Branco   +3 more
doaj   +1 more source

Increase of human platelet serotonin uptake by atypical histamine receptors

open access: yes, 1994
Histamine and the guanosine 3',5'-cyclic monophosphate (cGMP)-inducing agent sodium nitroprusside both increased serotonin (5-HT) uptake and cGMP levels in isolated human platelets in vitro.
C. Gespach   +6 more
core   +1 more source

Histamine, histamine receptors, and neuropathic pain relief [PDF]

open access: yes
Histamine, acting via distinct histamine H1 , H2 , H3 , and H4 receptors, regulates various physiological and pathological processes, including pain. In the last two decades, there has been a particular increase in evidence to support the involvement of ...
Telezhkin V   +3 more
core  

Radioligandbindungsstudien : Struktur-Wirkungs-Beziehungen von Antagonisten an muskarinischen, serotonergen und histaminergen Rezeptor-Subtypen

open access: yes, 2008
GPCRs and ligand-gated ion channels mediate a great variety of physiological effects within the human brain and periphery. The search for selective ligands at these target sites as pharmacological tools or new drug candidates is of great interest.
Linder, Matthias
core  

Efeito hiponociceptivo da histamina intra-articular [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2009.Histamina é encontrada no líquido sinovial de pacientes indivíduos saudáveis e em diversos ...
Silva, Eduardo Souza
core  

The dopaminergic system is able to modulate the central histamine-induced pressor effect in hemorrhage-shocked rats

open access: yesAnnales Academiae Medicae Silesiensis
Introduction: Histamine administered intracerebroventricularly (icv) induces a resuscitating effect in hemorrhage-shocked rats. Dopamine receptors are present in neuronal pathways involved in central cardiovascular regulation; therefore, the aim of the ...
Karolina Jasikowska   +5 more
doaj   +1 more source

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