Results 41 to 50 of about 10,364 (172)

Characterization of Human Group 9 Innate Lymphoid Cells in Response to Allergen Immunotherapy in Patients With Allergic Rhinitis

Allergy, EarlyView.
We aimed to report the existence and profile of group 9 innate lymphoid cells (ILC9s). Overall, ILC9 proportions in AR patients show differences compared to healthy subjects and responder SCIT patients. IL‐9 expression decreases after siRNA inhibition of Bach2 suggesting Bach2 could display as a transcription factor of ILC9.
Ya‐Qi Peng, Te Zhang, Xiao‐Qing Liu, Ismail Ogulur, Qi Sun, Beate Ruckert, Bi‐Xin He, De‐Hua Chen, Hideaki Morita, Hui‐Jing Ye, Qing‐Ling Fu, Cezmi A. Akdis   +11 more
wiley   +1 more source

Histamine Regulates the Inflammatory Profile of SOD1-G93A Microglia and the Histaminergic System Is Dysregulated in Amyotrophic Lateral Sclerosis

Frontiers in Immunology, 2017
Amyotrophic lateral sclerosis (ALS) is a late-onset motor neuron disease where activated glia release pro-inflammatory cytokines that trigger a vicious cycle of neurodegeneration in the absence of resolution of inflammation.
Savina Apolloni, Paola Fabbrizio, Paola Fabbrizio, Susanna Amadio, Giulia Napoli, Veronica Verdile, Giovanna Morello, Rosario Iemmolo, Eleonora Aronica, Sebastiano Cavallaro, Cinzia Volonté, Cinzia Volonté   +11 more
doaj   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Role of the Histaminergic System in the Inhibitory Effect of Melatonin on Broiler Chicken Feed Intake [PDF]

Poultry Science Journal
Prior investigations have postulated that melatonin, a prominent hormone produced by the pineal gland, can reduce animal food consumption. This study was designed to evaluate the involvement of central histamine H1 and H2 receptors in regulating ...
Majid Taati, Hassan Norouzian, Vahid Farhadi   +2 more
doaj   +1 more source

Histamine induced high mobility group box-1 release from vascular endothelial cells through H1 receptor

Frontiers in Immunology, 2022
BackgroundSystemic allergic reaction is characterized by vasodilation and vascular leakage, which causes a rapid, precipitous and sustained decrease in arterial blood pressure with a concomitant decrease of cardiac output.
Shangze Gao, Shangze Gao, Shangze Gao, Keyue Liu, Wenhan Ku, Dengli Wang, Hidenori Wake, Handong Qiao, Kiyoshi Teshigawara, Masahiro Nishibori   +9 more
doaj   +1 more source

Targeting the noradrenergic‐metabolic axis: A new strategy for sugar‐induced depression subtypes

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Lifestyle is closely related to major depressive disorder (MDD). Given the growing focus on the impact of diet on mental health, this study examined how dietary habits affect the pathophysiology of MDD. Experimental Approach Health check‐up data were analysed. Mice received sucrose under chronic unpredictable mild stress
Takatoshi Sakata, Kazuo Kunisawa, Masaya Hasegawa, Yumiko Seto, Aoi Ogawa, Hitomi Kurahashi, Yasuko Yamamoto, Masao Takemura, Hidetoshi Matunami, Tomoya Sugai, Noriki Kutsumura, Kuniaki Saito, Toshitaka Nabeshima, Akihiro Mouri   +13 more
wiley   +1 more source

Allergic Rhinoconjunctivitis: the Role of Histamine

Mediators of Inflammation, 1994
Allergic rhinoconjunctivitis is the most common atopic condition encountered in clinical practice. Analysis of the pathogenesis of this condition permits identification of optimal therapeutic targets.
M. Andersson, L. Greiff, C. Svensson
doaj   +1 more source

Protectin D1 and maresin 1 attenuate airway hyperreactivity induced by IL‐13 in human isolated small bronchi

British Journal of Pharmacology, EarlyView.
Background and Purpose Interleukin (IL)‐13 is implicated in airway hyperreactivity (AHR), a key feature of asthma. We explored the potential anti‐AHR activity of selected specialised pro‐resolving mediators (SPMs) in IL‐13‐induced AHR models, using human bronchial smooth muscle cells (BSMCs) and human isolated bronchi.
Willem Abma, Sven‐Erik Dahlén, Craig E. Wheelock, Mikael Adner, Mamdoh Al‐Amerie, Erik Sachs, Kasra Vali Jalali, Leonardo De Maria, Henric Olsson, Jesper Säfholm   +9 more
wiley   +1 more source

Combination of H1 and H2 Histamine Receptor Antagonists: Current Knowledge and Perspectives of a Classic Treatment Strategy

Life
Histamine receptor antagonists, which can bind to specific histamine receptors on target cells, exhibit substantial therapeutic efficacy in managing a variety of histamine-mediated disorders.
Erwen Kou, Xiaobei Zhang, Baiping Dong, Bo Wang, Yuanjie Zhu   +4 more
doaj   +1 more source

Histamina, receptores de histamina e anti-histamínicos: novos conceitos Histamine, histamine receptors and antihistamines: new concepts

Anais Brasileiros de Dermatologia, 2010
As drogas com ação anti-histamínica estão entre as medicações mais comumente prescritas na prática dermatológica diária, tanto em adultos como em crianças.
Paulo Ricardo Criado, Roberta Fachini Jardim Criado, Celina W. Maruta, Carlos d'Apparecida Machado Filho   +3 more
doaj   +1 more source