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Immunology of the Acetylcholine Receptor
Immunological Communications, 1976Myasthenia gravis is a spontaneously occurring autoimmune disease in which antibodies and lymphocytes are specifically reactive with nicotinic ACh receptors of skeletal muscle. Antibodies reactive with junctional receptors of human muscle are found in 90% of patients with myasthenia gravis and not at all in other diseases.
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Immunological studies of β‐adrenergic receptors
Journal of Cellular Biochemistry, 1983AbstractTwo types for antibodies have been raised against the β‐adrenergic receptor: either by injection of highly purified receptor from turkey erythrocytes or by injection of anticatecholamine ligand antibodies, and induction of anti‐idiotypic antibodies Our data illustrate the interactions of the β‐adrenergic receptor with these polyclonal ...
Arthur Donny Strosberg+6 more
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Immunological studies of acetylcholine receptors
Journal of Supramolecular Structure, 1976AbstractImmunochemical techniques for the study of acetylcholine receptors are described. Immunization of rabbits, rats, guinea pigs, and goats with acetylcholine receptor protein purified from Electrophorus electric organ tissue results in muscular weakness and death due to impaired neuromuscular transmission.
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Immunology of bile acids regulated receptors
Progress in Lipid ResearchBile acids are steroids formed at the interface of host metabolism and intestinal microbiota. While primary bile acids are generated in the liver from cholesterol metabolism, secondary bile acids represent the products of microbial enzymes. Close to 100 different enzymatic modifications of bile acids structures occur in the human intestine and ...
Fiorucci, Stefano+6 more
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Somatostatin receptor expression in clinical immunology
Metabolism, 1996Specific somatostatin receptors (ssts) have been described in normal and tumor tissues and identified on more than 95% of normal mitogen-activated human peripheral lymphocytes. Somatostatin may modulate the immune response by a variety of mechanisms, most of which are inhibitory, sst scintigraphy in patients with immune-mediated diseases revealed sst ...
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Immunological Properties of Fc Receptor on Lymphocytes
International Archives of Allergy and Immunology, 1981The present study was undertaken to clarify the function of FcRγ<sup>+</sup> and FcRγ<sup>––</sup> lymphocytes in anti-DNP IgE antibody responses. The helper activity was observed predominantly in FcRγ<sup>––</sup> T cells, but poorly in FcRγ<sup>+</sup> T cells, as in the case of IgG antibody responses ...
Muneo Miyama-Inaba+4 more
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Fc Receptors in Mucosal Immunology
2015Immunoglobulin A (IgA) is the most prevalent antibody class at mucosal surfaces. In addition to protecting mucosal surfaces by preventing invasion of pathogens, IgA can interact with multiple IgA receptors by binding to the Fc tail, carbohydrate side chains, or accessory molecules. The best characterized IgA Fc receptor is FcαRI (CD89), which acts as a
van Egmond, Marjolein+2 more
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Immunology of the Nicotinic Acetylcholine Receptor
1979The classical surface antigens of Enterobacteriaceae: 0, K, and H antigens have been studied extensively in the past and have provided a basis for the taxonomy of this family (Kauffmann, 1966, 1975). In comparison to the vast knowledge accumulated on the structure, localization, genetic determination, and biologic effects of O and K antigens (Weinbaum ...
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Immunological aspects of acetycholine receptors
Trends in Neurosciences, 1983Abstract Monoclonal antibodies raised against purified acetycholine receptor (AChR) can be used as probes for defining its structure and function, and, indirectly, for defining the binding sites of antibodies from patients with the muscle disease myasthenia gravis (MG).
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Immunological approaches for probing receptor structure and function
Trends in Pharmacological Sciences, 1991Molecular cloning has revealed the primary sequence of numerous membrane receptors, and this information catalysed two important efforts: modeling of receptor structure by hydropathy analysis and generating sequence-specific immunological probes with which these models can be tested experimentally.
Craig C. Malbon+2 more
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