Results 241 to 250 of about 113,576 (312)

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source

A case series of hypercalcemia associated with pembrolizumab therapy: evidence for a calcitriol-mediated mechanism. [PDF]

JCEM Case Rep
Belcher V, Barghouthi N, Hadique S, Woomer H, Wong Z, Haider A.   +5 more
europepmc   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

Alopecia Areata and Atopic Dermatitis: Common Mechanisms and Emerging Therapeutics. [PDF]

J Inflamm Res
Tang A, Rachko G, Manzo Margiotta F, Levine J, Del Duca E, Ungar B.   +5 more
europepmc   +1 more source

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

Advanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava, Alireza Rafieerad, Weiang Yan, Keshav Narayan Alagarsamy, Qingdong Guan, Leena Regi Saleth, Michel Aliani, Sanjiv Dhingra   +7 more
wiley   +1 more source

Immunopathogenesis of Sarcoidosis. [PDF]

Semin Respir Crit Care Med
Vagts C, Ascoli C, Jacobson JR.
europepmc   +1 more source

Liver Sinusoidal Endothelial Cells and Their Regulation of Immunology, Collagenization, and Bioreactivity in Fatty Liver: A Narrative Review. [PDF]

Int J Mol Sci
Abdulmajeed RJ, Sergi CM.
europepmc   +1 more source

Etoposide Hypersensitivity Reactions in Pediatric Oncology: Understanding Mechanisms and Optimizing Management. [PDF]

Cancers (Basel)
Filippo M, Zicari AM, Cinicola BL, Capponi M, Granata L, Stefanachi F, Carosini S, Ferrozzi F, Amoroso L.   +8 more
europepmc   +1 more source

Mannose receptor contributes to preferential oligomannosidic glycoform clearance in a murine pharmacokinetics model. [PDF]

MAbs
Falck D, Gijze S, Wasynczuk AM, Malik S, Tridon A, Lechmann M, Wuhrer M, Reusch D.   +7 more
europepmc   +1 more source

Peroxiredoxin 1, pyroptosis, and the emerging frontier in colorectal cancer therapy. [PDF]

World J Gastroenterol
Maurya DK.
europepmc   +1 more source