Results 251 to 260 of about 636,775 (308)

New immunology—immunology of pattern recognition receptors

Biology Bulletin, 2006
Pattern recognition receptors (PRRs) have been found on all cells of the body—cells of the innate and adaptive immune systems, epithelial and endothelial cells, keratinocytes, etc. PRRs can recognize specific molecular structures of microorganisms as well as allergens and other substances.
K. A. Lebedev, I. D. Ponyakina
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The Immunology of the Insulin Receptor

Immunological Communications, 1976
We have detected and characterized anti-insulin-receptor autoantibodies which circulate in several patients with insulin resistance diabetes. These antibodies are predominantly IgG and are polyclonal. They inhibit insulin binding to its receptor on a variety of tissues from widely separated species. Antibodies obtained from different patients appear to
J S, Flier, C R, Kahn, D B, Jarrett, J, Roth   +3 more
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THE ONTOGENY OF IMMUNOLOGICAL RECEPTORS IN THE THYMUS

Acta Pathologica Microbiologica Scandinavica Series C: Immunology, 1982
Receptors for sheep erythrocytes, for the Fc part of IgG (FcyR) and IgM (FcμR), and for components of activated human complement C3 (C3bR and C3dR) in thymus tissue from fetuses, infants and children were studied using haemadsorption to cryostat sections in a closed chamber.
N E, Gilhus, S, Frostad, R, Matre, O, Tönder   +3 more
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Engineered bacterial receptors in immunology

Current Opinion in Immunology, 1993
Gram-positive surface receptors, such as staphylococcal protein A ans streptococcal protein G, have been genetically engineered for many applications in the field of immunology, including detection antigens, affinity purification of fusion proteins and display of heterologous epitopes on the surface of bacterial cells.
S, Ståhl, P A, Nygren, A, Sjölander, M, Uhlén   +3 more
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Antigen-receptor degeneracy and immunological paradigms

Molecular Immunology, 2004
This paper discusses some consequences of the discovery that antigen receptors are degenerate: Immune specificity, in contrast to the tenets of the clonal selection paradigm, must be generated by the immune response down-stream of initial antigen recognition; and specificity is a property of a collective of cells and not of single clones.
Irun R, Cohen, Uri, Hershberg, Sorin, Solomon   +2 more
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Immunological studies of β‐adrenergic receptors

Journal of Cellular Biochemistry, 1983
AbstractTwo types for antibodies have been raised against the β‐adrenergic receptor: either by injection of highly purified receptor from turkey erythrocytes or by injection of anticatecholamine ligand antibodies, and induction of anti‐idiotypic antibodies Our data illustrate the interactions of the β‐adrenergic receptor with these polyclonal ...
P O, Couraud, B Z, Lu, A, Schmutz, O, Durieu-Trautmann, C, Klutchko-Delavier, J, Hoebeke, A D, Strosberg   +6 more
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Immunological of the Thyrotropin Receptor

Immunological Communications, 1976
Antibodies to the thyrotropin receptor appear to be responsible for hyperthyroidism in Graves' disease. The antibodies, described as thyroid-stimulating antibodies (TSAb) mimic the effects of thyrotropin (TSH) by binding to the TSH receptor and activating adenylate cyclase.
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Immunology of the Acetylcholine Receptor

Immunological Communications, 1976
Myasthenia gravis is a spontaneously occurring autoimmune disease in which antibodies and lymphocytes are specifically reactive with nicotinic ACh receptors of skeletal muscle. Antibodies reactive with junctional receptors of human muscle are found in 90% of patients with myasthenia gravis and not at all in other diseases.
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Is schizophrenia an immunologic receptor disorder?

Medical Hypotheses, 1983
A model is proposed for an autoimmune etiology for schizophrenia. We propose that schizophrenia is a syndrome (not a disease). We suggest that autoantibodies (and/or cell-mediated immunity) directed against autologous neurotransmitter receptors are responsible for the ebb and flow of psychotic symptomatology.
H H, Fudenberg, H D, Whitten, E, Merler, O, Farmati   +3 more
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Immunological studies of acetylcholine receptors

Journal of Supramolecular Structure, 1976
AbstractImmunochemical techniques for the study of acetylcholine receptors are described. Immunization of rabbits, rats, guinea pigs, and goats with acetylcholine receptor protein purified from Electrophorus electric organ tissue results in muscular weakness and death due to impaired neuromuscular transmission.
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