Results 261 to 270 of about 114,140 (294)

Immunological studies of β‐adrenergic receptors

Journal of Cellular Biochemistry, 1983
AbstractTwo types for antibodies have been raised against the β‐adrenergic receptor: either by injection of highly purified receptor from turkey erythrocytes or by injection of anticatecholamine ligand antibodies, and induction of anti‐idiotypic antibodies Our data illustrate the interactions of the β‐adrenergic receptor with these polyclonal ...
P O, Couraud, B Z, Lu, A, Schmutz, O, Durieu-Trautmann, C, Klutchko-Delavier, J, Hoebeke, A D, Strosberg   +6 more
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Antigen-receptor degeneracy and immunological paradigms

Molecular Immunology, 2004
This paper discusses some consequences of the discovery that antigen receptors are degenerate: Immune specificity, in contrast to the tenets of the clonal selection paradigm, must be generated by the immune response down-stream of initial antigen recognition; and specificity is a property of a collective of cells and not of single clones.
Irun R, Cohen, Uri, Hershberg, Sorin, Solomon   +2 more
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Immunological of the Thyrotropin Receptor

Immunological Communications, 1976
Antibodies to the thyrotropin receptor appear to be responsible for hyperthyroidism in Graves' disease. The antibodies, described as thyroid-stimulating antibodies (TSAb) mimic the effects of thyrotropin (TSH) by binding to the TSH receptor and activating adenylate cyclase.
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Immunology of the Acetylcholine Receptor

Immunological Communications, 1976
Myasthenia gravis is a spontaneously occurring autoimmune disease in which antibodies and lymphocytes are specifically reactive with nicotinic ACh receptors of skeletal muscle. Antibodies reactive with junctional receptors of human muscle are found in 90% of patients with myasthenia gravis and not at all in other diseases.
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Immunological studies of acetylcholine receptors

Journal of Supramolecular Structure, 1976
AbstractImmunochemical techniques for the study of acetylcholine receptors are described. Immunization of rabbits, rats, guinea pigs, and goats with acetylcholine receptor protein purified from Electrophorus electric organ tissue results in muscular weakness and death due to impaired neuromuscular transmission.
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Is schizophrenia an immunologic receptor disorder?

Medical Hypotheses, 1983
A model is proposed for an autoimmune etiology for schizophrenia. We propose that schizophrenia is a syndrome (not a disease). We suggest that autoantibodies (and/or cell-mediated immunity) directed against autologous neurotransmitter receptors are responsible for the ebb and flow of psychotic symptomatology.
H H, Fudenberg, H D, Whitten, E, Merler, O, Farmati   +3 more
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Immunology of bile acids regulated receptors

Progress in Lipid Research
Bile acids are steroids formed at the interface of host metabolism and intestinal microbiota. While primary bile acids are generated in the liver from cholesterol metabolism, secondary bile acids represent the products of microbial enzymes. Close to 100 different enzymatic modifications of bile acids structures occur in the human intestine and ...
Fiorucci, Stefano, Marchianò, Silvia, Urbani, Ginevra, Di Giorgio, Cristina, Distrutti, Eleonora, Zampella, Angela, Biagioli, Michele   +6 more
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Immunology of the Nicotinic Acetylcholine Receptor

1979
The classical surface antigens of Enterobacteriaceae: 0, K, and H antigens have been studied extensively in the past and have provided a basis for the taxonomy of this family (Kauffmann, 1966, 1975). In comparison to the vast knowledge accumulated on the structure, localization, genetic determination, and biologic effects of O and K antigens (Weinbaum ...
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Somatostatin receptor expression in clinical immunology

Metabolism, 1996
Specific somatostatin receptors (ssts) have been described in normal and tumor tissues and identified on more than 95% of normal mitogen-activated human peripheral lymphocytes. Somatostatin may modulate the immune response by a variety of mechanisms, most of which are inhibitory, sst scintigraphy in patients with immune-mediated diseases revealed sst ...
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Immunological approaches for probing receptor structure and function

Trends in Pharmacological Sciences, 1991
Molecular cloning has revealed the primary sequence of numerous membrane receptors, and this information catalysed two important efforts: modeling of receptor structure by hydropathy analysis and generating sequence-specific immunological probes with which these models can be tested experimentally.
S W, Bahouth, H Y, Wang, C C, Malbon
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