Results 271 to 280 of about 114,140 (294)
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Fc Receptors in Mucosal Immunology
2015Immunoglobulin A (IgA) is the most prevalent antibody class at mucosal surfaces. In addition to protecting mucosal surfaces by preventing invasion of pathogens, IgA can interact with multiple IgA receptors by binding to the Fc tail, carbohydrate side chains, or accessory molecules. The best characterized IgA Fc receptor is FcαRI (CD89), which acts as a
van Egmond, Marjolein +2 more
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Immunological functions of the neuropilins and plexins as receptors for semaphorins
Nature Reviews Immunology, 2013Semaphorins were originally identified as axon-guidance molecules that function during neuronal development. However, cumulative evidence indicates that semaphorins also participate in immune responses, both physiological and pathological, and they are now considered to be potential diagnostic and/or therapeutic targets for a range of diseases.
Atsushi, Kumanogoh, Hitoshi, Kikutani
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Immunological aspects of acetycholine receptors
Trends in Neurosciences, 1983Abstract Monoclonal antibodies raised against purified acetycholine receptor (AChR) can be used as probes for defining its structure and function, and, indirectly, for defining the binding sites of antibodies from patients with the muscle disease myasthenia gravis (MG).
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UP-REGULATION OF LACTOGENIC RECEPTORS - AN IMMUNOLOGICAL ARTIFACT?
Endocrinology, 1982We examined whether injection of heterologous hormones for more than one week might evoke a humoral immune response which would simulate receptor induction. Male rats were injected daily for ten days with human growth hormone (hGH) or ovine prolactin (oPRL), and binding of 125I-hGH and 125I-oPRL was examined in serum and in membranes from liver and ...
J P, Hughes, H P, Elsholtz, H G, Friesen
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Immunological role of TAM receptors in the cancer microenvironment
2020TAM receptors belong to the family of receptor tyrosine kinases, comprising of Tyro3, Axl and Mertk receptors (TAMs) and are important homeostatic regulators of inflammation in higher eukaryotes. Along with their ligands, Gas6 and ProteinS, TAMs acts as receptors to phosphatidylserine (PtdSer), an anionic phospholipid that becomes externalized on the ...
Varsha, Gadiyar +2 more
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Immunological Properties of Fc Receptor on Lymphocytes
International Archives of Allergy and Immunology, 1981The present study was undertaken to clarify the function of FcRγ<sup>+</sup> and FcRγ<sup>––</sup> lymphocytes in anti-DNP IgE antibody responses. The helper activity was observed predominantly in FcRγ<sup>––</sup> T cells, but poorly in FcRγ<sup>+</sup> T cells, as in the case of IgG antibody responses ...
Muneo Miyama-Inaba +4 more
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Immunologic Analysis of the Acetylcholine Receptor
1986Studies of receptors have come a long way in the past decade or so. It is no longer possible to study their pharmacological or electrophysiological properties without serious consideration of their macromolecular properties. A cascade of new techniques (e.g., affinity labeling, affinity purification, reconstitution, patch clamping, monoclonal antibody ...
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Immunological Analysis of the Avian Progesterone Receptor
1987Although the avian progesterone receptor has been purified and investigated extensively, its structure and composition remain unclear. The nontransformed receptor in cytosol extracts exists as two major forms, I and II, which differ in size and in ionic properties (1,2).
D. O. Toft +4 more
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Principles of Immunological Tolerance and Immunocyte Receptor Blockade
1974Publisher Summary This chapter discusses the principles of immunological tolerance and immunocyte receptor blockade. The problem of immunologic tolerance is examined from two perspectives. First, from the viewpoint of the susceptible thymus-derived (T) or bone marrow-derived (B) lymphoid cel, four possible ways of achieving insusceptibility to ...
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Chemokines and chemokine receptors in hematopoiesis and immunology
Experimental Hematology, 2006openaire +2 more sources