Peroxisome proliferator-activated receptor agonists (PPARs): a promising prospect in the treatment of psoriasis and psoriatic arthritis [PDF]
Anais Brasileiros de Dermatologia, 2013 Psoriasis is a polygenic, inflammatory and progressive disease, characterized by an abnormal differentiation and hyperproliferation of keratinocytes, associated with impaired immunologic activation and systemic disorders, while psoriatic arthritis is a ...
Emerson de Andrade Lima +5 more
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Treatment of Adult Patients with Relapsed/Refractory B-Cell Philadelphia-Negative Acute Lymphoblastic Leukemia [PDF]
, 2019 The majority of adult patients affected by B-cell acute lymphoblastic leukemia (B-ALL) will relapse after an initial response, while approximately 20% will display primary resistant disease. Patients suffering from relapsed/refractory B-ALL have a very
Lanza, Francesco +2 more
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Anaesthetic Management of Myasthenia Gravis with Thymic Mass in Facial Trauma [PDF]
The Indian Anaesthetists' Forum, 2010 Myasthenia gravis is an immunologic disorder characterised by polyclonal antibodies directed against nicotinic acetylcholine receptors at postneuromuscular junction.
Deepak Sharma, Dheer Singh
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HLA-G: An Important Mediator of Maternal-Fetal Immune-Tolerance
Frontiers in Immunology, 2021 Maternal-fetal immune-tolerance occurs throughout the whole gestational trimester, thus a mother can accept a genetically distinct fetus without immunological aggressive behavior.
Baimei Zhuang +4 more
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Frontiers in Immunology, 2017 The gut microbiota is essential for the development and regulation of the immune system and the metabolism of the host. Germ-free animals have altered immunity with increased susceptibility to immunologic diseases and show metabolic alterations. Here, we
Martina Spiljar +5 more
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Diagnostic Value Parameters Of Acute Phase Reactances Of Infectious-inflammatory Process In Diagnostics Of Early Neonatal Sepsis [PDF]
, 2018 An advanced progress of clinical neonatology in recent years has enabled to achieve considerable success in newborn management with due respect to both medical treatment and general care, especially in the group of neonates with low body weight at birth.
Bezrukov, L. (Leonid) +2 more
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Allergy Takes its Toll: The Role of Toll-like Receptors in Allergy Pathogenesis
World Allergy Organization Journal, 2008 Reduced early microbial exposure in early life has become a leading candidate to explain the escalating rate of allergic disease and has generated intense interest in the interaction between the developing immune system and the microbial environment ...
Susan L. Prescott, MD, PhD, FRACP
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Toll‐like receptors in pathogenesis of neurodegenerative diseases and their therapeutic potential
Immunity, Inflammation and Disease, 2023 Toll‐like receptors (TLRs) are a family of pattern‐recognition receptors triggered by pathogen‐derived and tissue‐damage‐related ligands. TLRs were previously believed to only be expressed in immune cells.
Yosef Tsegaye Dabi +2 more
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DR-bearing T lymphocytes in thoracic duct lymph [PDF]
, 1981 T cells having DR antigens were shown to be present in high numbers in the thoracic duct lymph of patients undergoing long-term drainage. As drainage progresses the proportion of T DR cells in the lymph increases to levels as high as 70% at 6 weeks ...
Abo +25 more
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Liver Research, 2023 Alcohol-related liver disease (ALD) became an important health issue worldwide. Following chronic alcohol consumption, the development of ALD might be caused by metabolic and immunologic factors, such as reactive oxygen species (ROS) and pro-inflammatory
Tom Ryu +4 more
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