Results 91 to 100 of about 478,975 (311)

In vitro initial immune response against Leishmania amazonensis infection is characterized by an increased production of IL-10 and IL-13

Brazilian Journal of Infectious Diseases, 2010
The initial encounter of Leishmania with its host's immune system is important in the outcome of infection. Previous studies have shown that PBMCs from healthy volunteers (HV) exposed to Leishmania differ in IFN-γ production.
Zirlane Castelo B. Coêlho, Maria Jania Teixeira, Erika Freitas Mota, Mércia Sindeaux Frutuoso, João Santana da Silva, Aldina Barral, Manoel Barral-Netto, Margarida Maria L. Pompeu   +7 more
doaj   +1 more source

Schizophrenia is a TH2 dominant autoimmune disease possibly against acetylcholine receptors of CNS [PDF]

, 2012
Schizophrenia is a very common psychiatric disorder. However, its etiology and pathogenesis is still unknown. Current theory saying that neurotransmitter imbalance such as serotonin or dopamine only provides limited effectiveness in schizophrenia ...
Wanchung(Wan-Jiung) Hu
core   +1 more source

Cytokine tuning of intestinal epithelial function [PDF]

, 2018
The intestine serves as both our largest single barrier to the external environment and the host of more immune cells than any other location in our bodies.
Andrews, Caroline, Durum, Scott K., McLean, Mairi H.   +2 more
core   +4 more sources

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Interleukin-1 beta-induced up-regulation of opioid receptors in the untreated and morphine-desensitized U87 MG human astrocytoma cells

Journal of Neuroinflammation, 2012
Background Interleukin-1beta (IL-1β) is a pro-inflammatory cytokine that can be produced in the central nervous system during inflammatory conditions. We have previously shown that IL-1β expression is altered in the rat brain during a morphine tolerant ...
Byrne Linda, Peng Jinsong, Sarkar Sraboni, Chang Sulie L   +3 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Glucocorticoids—All-Rounders Tackling the Versatile Players of the Immune System [PDF]

, 2019
Glucocorticoids regulate fundamental processes of the human body and control cellular functions such as cell metabolism, growth, differentiation, and apoptosis.
Agarwal, Al-Mousawi, Allen, Almawi, Anderson, Andreae, Annunziato, Anthony, Arya, Avnir, Avnir, Baatjes, Banchereau, Banuelos, Banuelos, Barnes, Beck, Beck, Belvisi, Bengtsson, Benson, Bentley, Berdeli, Blotta, Borish, Brack, Bradding, Braun, Brozek, Burger, Buttgereit, Buttgereit, Buttgereit, Capell, Chan, Chatham, Chen, Choo, Chung, Clutterbuck, Cohn, Corbera-Bellalta, Cosmi, Cosmi, Crocker, Cronstein, Damsker, Dao Nguyen, Daynes, Daynes, de Castro Kroner, Deng, Dolhain, Dorner, Dougherty, Durham, Eichenauer, Eichhorst, Eklund, Erin, Espigol-Frigole, Fanouriakis, Finotto, Firestein, Firestein, Franchimont, Franchimont, Franco, Gao, Geginat, Gemou-Engesaeth, Gladman, Gomes, Gracie, Gregersen, Greiner, Grindebacke, Guiducci, Gupta, Hadji, Hagan, Hahn, Hamid, Hamid, Hanahan, Haneda, Hartl, Hasegawa, Hawrylowicz, Hehlmann, Heidari, Heiman, Hellmich, Hermann-Kunz, Hernandez-Rodriguez, Hicsonmez, Hirahara, Hoelzer, Hollenberg, Hu, Hussain, Hutchison, Inaba, Ismaili, Jacobi, Jacobi, Jee, Jennette, Jiang, Jin, Jing, John, Jones, Jones, Kansal, Kaplan, Karagiannidis, Kirwan, Klarenbeek, Klassen, Kleiman, Klein, Klimek, Kotake, Kotake, Kovalovsky, Kremer, Kruth, Leppert, Li, Li-Weber, Liberman, Liles, Lim, Lin, Linden, Liu, Loetscher, Lohse, Lugar, Luo, Machold, Maggi, Maneechotesuwan, Manzoni, Martinez-Sanchez, Maruotti, Matsui, Matteson, McDonough, Meagher, Mercieca, Merrill, Miller, Miltenburg, Mitra, Miyasaka, Miyaura, Moallem, Morita, Moynihan, Mozo, Muehling, Munck, Muraro, Murphy, Naseer, Neeck, Neeck, Nicholson, O'Byrne, O'Byrne, Oakley, Oakley, Ochiai, Odendahl, Oppong, Ospelt, Parrillo, Patel, Pawankar, Pearson, Perez-Guerrero, Pers, Picchianti-Diamanti, Pratt, Pratt, Pui, Qin, Quinn, Radich, Rainer, Rak, Ramirez, Rank, Ratman, Refojo, Reichardt, Rider, Ring, Robinson, Robinson, Ronnblom, Ruiz-Arruza, Saadoun, Sallusto, Samson, Samson, Santos, Schacke, Schacke, Scherlinger, Schmitz, Schug, Shah, Shaw, Shlomchik, Siegel, Smith, Smolen, Smolen, Song, Stahn, Stahn, Stellato, Stone, Strehl, Strehl, Tanaka, Terrades-Garcia, Theofilopoulos, Thomas, Thomas, Till, Tuckermann, Turjeman, Ulmansky, Umetsu, van der Geest, van Oosterhout, Vandevyver, Verhoef, Verstappen, von Bernus, von Hertzen, Waknine-Grinberg, Walker, Wang, Wassenberg, Watanabe, Wen, Weyand, Weyand, Wheatley, Wikstrom, Willemze, Wills-Karp, Wills-Karp, Wollenberg, Wollenberg, Wright, Wu, Wuthrich, Xystrakis, Yamamoto, Yan, Yang, Ying, Zubiaga   +268 more
core   +1 more source

[Interleukin 12 (IL-12) and its receptor].

Postepy higieny i medycyny doswiadczalnej, 2002
This article reviews of recent data on the structure of IL-12 and the function of its receptor (IL-12R). It presents a new opinion on the role of its subunits in the cytokine activity and on the signal transmission via IL-12R in the process of cell activation by IL-12.
Jacek, Szeliga, Teresa, Gościcka
openaire   +1 more source

Remarkable Recovery After Delayed High‐Dose Methylprednisolone in a Rare Case of Penetrating Spinal Cord Injury

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Traumatic spinal cord injury (TSCI) caused by sharp‐force penetration is exceptionally rare, and the use of high‐dose methylprednisolone (MP) remains highly controversial, especially beyond the conventional 8‐h treatment window. This case report describes a 30‐year‐old male with acute incomplete TSCI following a knife stab wound to the right ...
Honghong Wang, Shuang Liu, Jiale Wang, Kaiyang Xue, Shenwei Li, Zhongheng Du   +5 more
wiley   +1 more source

Single‐cell analysis of tumor microenvironment and cell adhesion reveals that interleukin‐1 beta promotes cancer cell proliferation in breast cancer

Animal Models and Experimental Medicine
Background Triple‐negative breast cancer (TNBC), which is so called because of the lack of estrogen receptors (ER), progesterone receptors (PR), and human epidermal growth factor receptor 2 (HER2) receptors on the cancer cells, accounts for 10%–15% of ...
Wenyan Wang, Gehong Dong, Ziguo Yang, Shaoxiang Li, Jia Li, Lin Wang, Qiang Zhu, Yuchen Wang   +7 more
doaj   +1 more source