Results 91 to 100 of about 446,676 (208)

Sex-dependent regulation of mucin gene transcription and airway secretion and mechanics following intra-airway IL-13 in mice with conditional loss of club cell Creb1

Frontiers in Physiology
Introduction: Interleukin 13 (IL-13) is an important effector molecule in allergic asthma. IL-13-mediated mucin hypersecretion requires conversion of secretoglobin-positive club cells into goblet cells through suppression of forkhead box A2 (FOXA2) and ...
Mariana Sponchiado, Amy Fagan, Luz Mata, Angelina L. Bonilla, Pedro Trevizan-Baú, Sreekala Prabhakaran, Leah R. Reznikov   +6 more
doaj   +1 more source

Updated Evaluation of Dupilumab in the Treatment of Asthma: Patient Selection and Reported Outcomes

Therapeutics and Clinical Risk Management, 2020
G Daniel Brooks The Asthma and Allergy Center, Bellevue, NE, USACorrespondence: G Daniel BrooksThe Asthma and Allergy Center, 3503 Samson Way, Suite 108, Bellevue, NE 68123, USATel +1-402-592-2055Fax +1-402-592-2419Email gdbrooks@asthmaandallergycenter ...
Brooks GD
doaj  

Distinctive growth requirements and gene expression patterns distinguish progenitor B cells from pre-B cells. [PDF]

, 1993
Long-term bone marrow cultures have been useful in determining gene expression patterns in pre-B cells and in the identification of cytokines such as interleukin 7 (IL-7).
Faust, EA, Saffran, DC, Toksoz, D, Williams, DA, Witte, ON   +4 more
core  

Expression of Interleukin-13 Receptor Alpha 2 in Brainstem Gliomas

Cancers
The objective of this study was to investigate IL13Ra2 expression in brainstem glioma (BSG) and its correlation with key markers, functions, and prognostic implications, evaluating its therapeutic potential. A total of 80 tumor samples from BSG patients were analyzed. Multiplex immunofluorescence was used to examine six markers—IL13Ra2, H3.3K27M, CD133,
Xiaoou Li, Xiong Xiao, Yi Wang, Guocan Gu, Tian Li, Yi Wang, Chunzhao Li, Peng Zhang, Nan Ji, Yang Zhang, Liwei Zhang   +10 more
openaire   +2 more sources

Characterization of the Interaction between Interleukin-13 and Interleukin-13 Receptors

Characterization of the Interaction between Interleukin-13 and Interleukin-13 Receptors
論文(Article)
  +3 more sources

The Role of Alarmins in the Pathogenesis of Asthma

Biomolecules
Asthma is defined as a chronic respiratory disease, the processes of which are mainly related to the hyperreactivity of the immune system. Airway hyperresponsiveness and remodeling are other hallmarks of asthma that are strongly involved in the ...
Paulina Plewa, Julia Pokwicka, Estera Bakinowska, Kajetan Kiełbowski, Andrzej Pawlik   +4 more
doaj   +1 more source

Case Series: Combination of dupilumab and omalizumab as a way to reduce dupilumab-associated adverse events in severe atopic dermatitis

Frontiers in Allergy
Dupilumab is a fully human monoclonal antibody directed against the interleukin-4 receptor subunit α, the common chain of the IL-4 and IL-13 receptors.
Daria S. Fomina, Daria S. Fomina, Olga A. Mukhina, Olga A. Mukhina, Elizaveta L. Sedova, Marina S. Lebedkina, Elena N. Bobrikova, Alexander V. Karaulov, Mariana A. Lysenko, Mariana A. Lysenko, Mariana A. Lysenko, Harald Renz, Harald Renz   +12 more
doaj   +1 more source

Interleukin-1 Receptor Antagonist Has a Novel Function in the Regulation of Matrix Metalloproteinase-13 Expression.

PLoS ONE, 2015
Interleukin-1 receptor antagonist (IL-1Ra) is an IL-1 family member, which binds to IL-1 receptors but does not induce any intracellular signaling. We addressed whether IL-1Ra has a novel function in regulation of the extracellular matrix or adhesion ...
Hisashi Goto, Yuichi Ishihara, Takeshi Kikuchi, Ario Izawa, Nobuaki Ozeki, Eijiro Okabe, Yosuke Kamiya, Yusuke Ozawa, Hiroki Mizutani, Genta Yamamoto, Makio Mogi, Kazuhiko Nakata, Hatsuhiko Maeda, Toshihide Noguchi, Akio Mitani   +14 more
doaj   +1 more source

Identification of potential hub genes associated with atopic dermatitis-like recombinant human epidermal model using integrated transcriptomic and proteomic analysis

Biomolecules & Biomedicine
Atopic dermatitis (AD) is a severe inflammatory skin disorder, characterized by elevated levels of proinflammatory cytokines that fuel a vicious cycle of inflammation.
Wu Qiao, Tong Xie, Jing Lu, Tinghan Jia, Ken Kaku   +4 more
doaj   +1 more source

The Interleukin 13 Receptor Complex [PDF]

STEM CELLS, 2000
openaire   +2 more sources