Results 231 to 240 of about 268,441 (265)

Interleukin-13 receptor as a unique target for anti-glioblastoma therapy

International Journal of Cancer, 2001
Surgery, radiotherapy and chemotherapy have minimally altered survival of glioblastoma patients. We explored a specific approach for glioblastoma therapy in which cellular interleukin-13 (IL-13) receptors were targeted by an IL-13 cytotoxin. A wide array of human glioblastoma cell lines expressing the receptor for IL-13 were effectively killed by an IL-
S R, Husain, B H, Joshi, R K, Puri
openaire   +2 more sources

The interleukin-4/interleukin-13 receptor of human synovial fibroblasts: overexpression of the nonsignaling interleukin-13 receptor alpha2.

Laboratory investigation; a journal of technical methods and pathology, 1998
Interleukin (IL)-4 and IL-13 are known to bind to shared heteromultimeric receptor complexes of variable composition. Given the many regulatory effects of IL-4 and IL-13 on synovial cells, we aimed to characterize their IL-4/IL-13 receptor (R). Cultivated synovial fibroblasts expressed transcripts for IL-4Ralpha and IL-13Ralpha1, the human homolog of ...
N, Feng, S M, Lugli, B, Schnyder, J F, Gauchat, P, Graber, E, Schlagenhauf, B, Schnarr, M, Wiederkehr-Adam, A, Duschl, M H, Heim, R A, Lutz, R, Moser   +11 more
openaire   +1 more source

Solution structure of interleukin-13 and insights into receptor engagement.

Journal of molecular biology, 2001
The complex and interrelated function of the interleukin cytokines relies on a range of pro-inflammatory and anti-inflammatory immune responses mediated by an array of receptors, and there is considerable cross-reactivity for related cytokines. Recent findings continue to elucidate the expression patterns of interleukin receptors associated with a ...
E Z, Eisenmesser, D A, Horita, A S, Altieri, R A, Byrd   +3 more
openaire   +1 more source

109 Lebrikizumab Allows Interleukin-13 Membrane Binding and Subsequent Internalization through the Decoy Receptor Interleukin-13 Receptor Alpha 2

Journal of Investigative Dermatology, 2022
I. Wulur, R.D. Van Horn, A. Ryuzoji, A.J. Okragly, C. Patel, R. Benschop   +5 more
openaire   +1 more source

Interleukin 13 and its Receptor

1998
Juha Punnonen, José M. Carballido, Gregorio Aversa, Jan E. de Vries   +3 more
openaire   +1 more source

Genetics and airway expression of interleukin-13 receptors in asthma [PDF]

, 2004
The primary objectives of this thesis were to examine the influence of polymorphisms in the IL-13RA1 and the IL13RA2 genes on the genetic susceptibility to asthma, and to evaluate the expression of IL-13 receptor subunits in the airways. Using solid-phase chemical cleavage of mismatches (SP-CCM), we screened the coding regions of IL13RA1 and IL13RA2 ...
openaire  

ESDR109 - Lebrikizumab Allows Interleukin-13 Membrane Binding and Subsequent Internalization through the Decoy Receptor Interleukin-13 Receptor Alpha 2

2022
Robert Benschop, Chetan Patel, Angela Okragly, Aya Ryuzoji, Robert Van Horn, Isabella Wulur   +5 more
openaire   +1 more source

Interleukin-22: Immunobiology and Pathology

Annual Review of Immunology, 2015
Jarrod Dudakov, Alan Hanash
exaly  

Historical overview of the interleukin-6 family cytokine

Journal of Experimental Medicine, 2020
Sujin Kang, Masashi Narazaki, Tadamitsu Kishimoto   +2 more
exaly  

[Interleukin-13 and interleukin-13 receptor in Hodgkin's disease].

Polskie Archiwum Medycyny Wewnetrznej, 2003
Zofia Monika, Rupniewska, Małgorzata, Wach   +1 more
openaire   +1 more source