Results 1 to 10 of about 1,187,146 (230)

IL‐31 and IL‐31 receptor alpha in pemphigus: Contributors to more than just itch?

The Journal of Dermatology, 2023
AbstractPemphigus is an autoimmune blistering disorder with four major subtypes: pemphigus vulgaris (PV), pemphigus vegetans (PVe), pemphigus foliaceus (PF), and pemphigus herpetiformis (PH). Among them, PF and PH present itching as a clinical feature; however, the mechanisms behind the pruritus are still unclear.
Satoshi Okuno, Takashi Hashimoto, Yuki Yamazaki, Manami Okuzawa, Takahiro Satoh   +4 more
openaire   +2 more sources

Implication of Increased Serum IL-31 for Primary Biliary Cholangitis

Immunological Investigations, 2020
Interleukin-31 (IL-31) has diverse biological functions. Increased IL-31 has been found in some skin and autoimmune diseases. There has been no study reporting the association between IL-31 and primary biliary cholangitis (PBC). This study was designed to determine serum IL-31 level and to explore its diagnostic value for PBC as well as the association
Ning, Mu, Feng, Lin, Zhiguo, Jiang, Yan, Liang, Zaixing, Yang   +4 more
openaire   +2 more sources

Increased tissue expression of IL-31 in patients with psoriasis

Cytokine
Psoriasis is a chronic inflammatory skin disease, and its pathogenesis remains unclear. Although many studies have demonstrated the role of serum interleukin-31 (IL-31) in psoriasis, only one study has examined histopathological expression in lesional skin.
Rachot, Wongjirattikarn, Nipon, Chaisuriya, Suteeraporn, Chaowattanapanit, Piti, Ungarreevittaya, Pirawan, Poosekeaw, Kengkart, Winaikosol, Charoen, Choonhakarn, Narachai, Julanon, Eakkapol, Utchariyaprasit, Kittisak, Sawanyawisuth   +9 more
openaire   +2 more sources

Analysis of the IL-31 pathway in Mycosis fungoides and Sézary syndrome

Archives of Dermatological Research, 2014
IL-31, predominantly produced by CD45RO + CLA + Th2 cells, plays an important pathogenetic role in pruritic skin diseases like atopic dermatitis. As tumor cells in Sézary syndrome (SS) and Mycosis fungoides (MF) possess similar immunophenotypes and the conditions mentioned are often associated with pruritus, the analysis of the IL-31 pathway in MF/SS ...
Markus, Möbs, Stefanie, Gryzik, Ahmed, Haidar, Daniel, Humme, Marc, Beyer, Staffan, Vandersee   +5 more
openaire   +2 more sources

“Luna Blu” il 31 agosto

2012
Come succede in media una volta ogni due anni e mezzo, questo mese ha non una ma due Lune piene, e la seconda per tradizione si chiama “blu”. Ma il colore non c'entra.
openaire   +1 more source

Structural insights into IL-31 signaling inhibition by a neutralizing antibody

Structure
Interleukin-31 (IL-31) signals through the IL-31 receptor alpha (IL-31RA) and oncostatin M receptor beta (OSMRβ) heterodimer, mediating pruritus, dermatitis, inflammatory responses, neuroimmune interactions, and certain cancers. Here, we present the crystal structure of canine IL-31 (cIL-31) in complex with a neutralizing caninized monoclonal antibody (
Tianling Guo, Yuxin Zheng, Zheng Fan, Ping Liu, Yan Chai, Xiaoping Liao, Caili Zhang, Xuefei Pang, Delin Li, Feng Gao, Haixia Xiao   +10 more
openaire   +2 more sources

Die Bedeutung des IL-31

Aktuelle Dermatologie, 2013
openaire   +1 more source

Correlation of IL-31 serum levels with severity of atopic dermatitis

Journal of Allergy and Clinical Immunology, 2008
Ulrike, Raap, Katja, Wichmann, Manuela, Bruder, Sonja, Ständer, Bettina, Wedi, Alexander, Kapp, Thomas, Werfel   +6 more
openaire   +2 more sources

IL-31 in patients with asthma and COPD

2018
openaire   +1 more source

Mit IL-31-Hemmung gegen Juckreiz

ästhetische dermatologie & kosmetologie
openaire   +1 more source